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Interleukin-18

Known as: IFN-gamma Inducing Factor, Interferon-gamma Inducing Factor, IL18 
A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Trauma remains a leading cause of death worldwide. Hemorrhagic shock and direct injury to vital organs are responsible for early… Expand
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Highly Cited
2003
Highly Cited
2003
Mesenchymal stem cells (MSCs) have been recently shown to inhibit T-cell proliferation to polyclonal stimuli. We characterized… Expand
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Review
2001
Review
2001
Although interleukin-18 is structurally homologous to IL-1 and its receptor belongs to the IL-1R/Toll-like receptor (TLR… Expand
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Review
2001
Review
2001
IL-18 is a potent proinflammatory cytokine able to induce IFNgamma, GM-CSF, TNFalpha and IL-1 in immunocompetent cells, to… Expand
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Review
1998
Review
1998
Publisher Summary Interleukin-18 (IL-18) is a multifunctional cytokine, the roles of which extend over both acquired and innate… Expand
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Highly Cited
1998
Highly Cited
1998
IL-18 is synthesized as a precursor molecule without a signal peptide but requires the IL-1beta converting enzyme (ICE, caspase-1… Expand
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Highly Cited
1997
Highly Cited
1997
Although highly active antiretroviral therapy (HAART) in the form of triple combinations of drugs including protease inhibitors… Expand
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Highly Cited
1997
Highly Cited
1997
Recent studies have identified several coreceptors that are required for fusion and entry of Human Immunodeficiency Virus type 1… Expand
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Highly Cited
1997
Highly Cited
1997
Culture conditions for human dendritic cells (DC) have been developed by several laboratories. Most of these culture methods… Expand
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Highly Cited
1996
Highly Cited
1996
T cell proliferation in vivo is presumed to reflect a T cell receptor (TCR)-mediated polyclonal response directed to various… Expand
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