Recombinant Interferon

Known as: Human Leukocyte Interferon, Interferons, IFN 
One of a group of recombinant therapeutic glycoprotein cytokines with antiviral, anti-proliferative, and immunomodulating activities. Interferons… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2018
020040019622018

Papers overview

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Review
2017
Review
2017
Rheumatoid arthritis is a chronic autoimmune disease that causes progressive articular damage, functional loss, and comorbidity… (More)
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Review
2017
Review
2017
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder affecting motor neurons, resulting in… (More)
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Review
2015
Review
2015
C-type lectin receptors (CLRs) are a large family of soluble and trans-membrane pattern recognition receptors that are widely and… (More)
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Highly Cited
2013
Highly Cited
2013
The presence of DNA in the cytoplasm of mammalian cells is a danger signal that triggers host immune responses such as the… (More)
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Highly Cited
2008
Highly Cited
2008
Toll-like receptor 4 (TLR4) induces two distinct signaling pathways controlled by the TIRAP-MyD88 and TRAM-TRIF pairs of adaptor… (More)
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Highly Cited
2006
Highly Cited
2006
The innate immune system senses viral infection by recognizing a variety of viral components (including double-stranded (ds)RNA… (More)
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Highly Cited
2005
Highly Cited
2005
Type I interferons are central mediators for antiviral responses. Using high-throughput functional screening of interferon… (More)
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Highly Cited
2004
Highly Cited
2004
Interferons (IFNs) are critical for protection from viral infection, but the pathways linking virus recognition to IFN induction… (More)
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Highly Cited
2001
Highly Cited
2001
Toll-like receptors (TLRs) are a family of innate immune-recognition receptors that recognize molecular patterns associated with… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Only 15 to 20 percent of patients with chronic hepatitis C have a sustained virologic response to interferon therapy… (More)
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