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Recombinant Interferon

Known as: Human Leukocyte Interferon, Human lymphoblastoid interferon, Interferons 
One of a group of recombinant therapeutic glycoprotein cytokines with antiviral, anti-proliferative, and immunomodulating activities. Interferons… 
National Institutes of Health

Related topics

Related topics

9 relations
IFN-DTIC RegimenIFNA1 geneInterferonInterferon Alfa-2b

Papers overview

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Highly Cited
2007
Highly Cited
2007
The Atg5–Atg12 conjugate associates with innate antiviral immune responses
Autophagy is an essential process for physiological homeostasis, but its role in viral infection is only beginning to be… 
Review
2006
Review
2006
Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors.
Induction of type I interferons (IFNs) by viruses and other pathogens is crucial for innate immunity, and it is mediated by the… 
Review
2006
Review
2006
Antiviral innate immunity pathways
Recent studies have uncovered two signaling pathways that activate the host innate immunity against viral infection. One of the… 
Highly Cited
2001
Highly Cited
2001
Impairment of Mycobacterial But Not Viral Immunity by a Germline Human STAT1 Mutation
Interferons (IFN) α/β and γ induce the formation of two transcriptional activators: gamma-activating factor (GAF) and interferon… 
Highly Cited
1995
Highly Cited
1995
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins.
Activation of early response genes by interferons (IFNs) requires tyrosine phosphorylation of STAT (signal transducers and… 
Review
1995
Review
1995
Role of interferons and other cytokines in the regulation of the immune response
Cytokines represent the major factors involved in the communication between T cells, macrophages and other immune cells in the… 
Highly Cited
1990
Highly Cited
1990
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.
A cytokine that can synergize with interleukin 2 to activate cytotoxic lymphocytes was purified to homogeneity. The protein… 
Review
1990
Review
1990
Haemopoietic receptors and helical cytokines.
Highly Cited
1988
Highly Cited
1988
IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.
The effect of human recombinant interleukin 4 (IL-4) on antibody production by normal peripheral blood mononuclear cells enriched… 
Highly Cited
1988
Highly Cited
1988
Interferons and other regulatory cytokines
From an Antiviral Factor to a Family of Multifunctional Cytokines The Interferon Gene Family Induction of IFN-+ga+n and IFN-+gb+n… 
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