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Recombinant Interferon

Known as: Human Leukocyte Interferon, Human lymphoblastoid interferon, Interferons 
One of a group of recombinant therapeutic glycoprotein cytokines with antiviral, anti-proliferative, and immunomodulating activities. Interferons… 
National Institutes of Health

Related topics

Related topics

9 relations
IFN-DTIC RegimenIFNA1 geneInterferonInterferon Alfa-2b

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
IFN-lambda: novel antiviral cytokines.
The first line of defense against viral infections is mediated by interferons (IFN)s, which are produced rapidly by the infected… 
Review
2003
Review
2003
Role of toll-like receptors and their adaptors in adjuvant immunotherapy for cancer.
The potentiation of immune responses to tumor-associated antigen (Ag) is a pivotal issue in immunotherapy for cancer and thus… 
Review
2002
Review
2002
Natural type I interferon-producing cells as a link between innate and adaptive immunity.
Review
2001
Review
2001
The Host-Pathogen Interaction New Themes from Dendritic Cell Biology
Highly Cited
2001
Highly Cited
2001
The rainbow trout (Oncorhynchus mykiss) Mx1 promoter. Structural and functional characterization.
Mx1 gene expression was studied in the rainbow trout (Oncorhynchus mykiss) gonad (RTG) (fibroblast) cell line. RT-PCR analyses… 
Highly Cited
1997
Highly Cited
1997
Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway
Activation of early response genes by interferons (IFNs) and other cytokines requires tyrosine phosphorylation of a family of… 
Highly Cited
1990
Highly Cited
1990
The human intracellular Mx‐homologous protein is specifically induced by type I interferons
The murine Mx‐1 protein is one of the best biochemically and functionally characterized interferon (IFN)‐induced proteins that is… 
Highly Cited
1983
Highly Cited
1983
A unique set of polypeptides is induced by γ interferon in addition to those induced in common with α and β interferons
Human immune interferon (IFN-γ) differs from leukocyte interferon (IFN-α) and fibroblast interferon (IFN-β) in cell origin… 
Highly Cited
1981
Highly Cited
1981
Antiviral activities of hybrids of two major human leukocyte interferons.
Four hybrid human leukocyte interferon (LeIF or IFN-alpha) genes have been constructed by in vitro recombination of LeIF-A (IFN… 
Highly Cited
1975
Highly Cited
1975
Characteristics of immune interferon produced by human lymphocyte cultures compared to other human interferons.
A factor with antiviral activity has been produced in vitro by combined macrophage-lymphocyte cultures from patients with recent… 
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