Skip to search formSkip to main contentSkip to account menu

Recombinant Human Endostatin

Known as: Endostatin, Recombinant Endostatin, rhEndostatin 
A recombinant human proteolytic fragment of the C-terminal end of type XVIII collagen. Endostatin induces microvascular endothelial cell apoptosis… 
National Institutes of Health

Related topics

Related topics

8 relations
Angiogenesis InhibitionApoptosisCOL18A1 geneEndostatin, human

Broader (1)

Endostatins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Low‐dose endostatin normalizes the structure and function of tumor vasculature and improves the delivery and anti‐tumor efficacy of cytotoxic drugs in a lung cancer xenograft murine model
Introduction:  To some extent endostatin normalizes tumor vasculature. However, the optimum time window and optimum drug dose for… 
2011
2011
Recombinant Human Endostatin Endostar Inhibits Tumor Growth and Metastasis in a Mouse Xenograft Model of Colon Cancer
To investigate the effects of recombinant human endostatin Endostar on metastasis and angiogenesis and lymphangiogenesis of… 
2011
2011
Effects of recombinant human endostatin on peritoneal angiogenesis in peritoneal dialysis rats
Aim:  To investigate the effects of recombinant human endostatin (Endostar) on peritoneum angiogenesis in a model of dialysate… 
2009
2009
N-terminal fragment of the anti-angiogenic human endostatin binds copper(II) with very high affinity.
2008
2008
Mechanism of Fibroblast‐Like Synoviocyte Apoptosis Induced by Recombinant Human Endostatin in Rats with Adjuvant Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by pronounced synovial hyperplasia, in which there may… 
Highly Cited
2004
Highly Cited
2004
Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer
Purpose: Recombinant human endostatin (rhES) is an antiangiogenic agent derived from collagen XVIII which inhibits tumor growth… 
2004
2004
Expression of recombinant endostatin in Agrobacterium-inoculated leaf disks of Nicotiana tabacum var. Xanthi
Recombinant endostatin was transiently expressed in Agrobacterium-inoculated leaf disks of Nicotiana tabacum var. Xanthi with a… 
2003
2003
Synergistic activity of recombinant human endostatin in combination with adriamycin: analysis of in vitro activity on endothelial cells and in vivo tumor progression in an orthotopic murine mammary…
PURPOSE Current combination treatment strategies in malignancy are designed to evaluate the use of cytotoxic drugs and… 
2001
2001
Circulating levels of endostatin in cancer patients.
Endostatin is a negative regulator of angiogenesis. We examined plasma endostatin levels (PESLs) in cancer patients and healthy… 
2001
2001
Optimal production and in vitro activity of recombinat endostatin from stably transformed Drosophila melanogaster S2 cells
SummaryRecombinant plasmids containing a complementary deoxyribonucleic acid coding mouse endostatin were transfected and stably… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)