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Endostatins

Known as: Endostatin, Endostatins [Chemical/Ingredient] 
Angiostatic proteins that are formed from proteolytic cleavage of COLLAGEN TYPE XVIII.
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (6)

AP25 peptideEndostatin, humanLDP-endostatin N-terminal fusion proteinRecombinant Human Endostatin

Broader (2)

Angiogenesis InhibitorsAntineoplastic Agents
COL18A1 geneCOL18A1 wt AlleleCollagen Type XVIIICollagen Type XVIII, alpha1 Subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Chronic type II diabetes mellitus leads to changes in neuropeptide Y receptor expression and distribution in human myocardial tissue.
Highly Cited
2006
Highly Cited
2006
Endostatin therapy reveals a U-shaped curve for antitumor activity
Developing continuous systemic delivery of endostatin has been a goal of many laboratories. We have employed a method of gene… 
Highly Cited
2004
Highly Cited
2004
Effects of Secreted Frizzled‐Related Protein 3 on Osteoblasts In Vitro
To examine if sFRP3s act as decoy receptors for Wnt, we examined the effects of recombinant sFRP3 on mouse osteoblast… 
2004
2004
A murine model of ex vivo angiogenesis using aortic disks grown in fibrin clot.
Highly Cited
2004
Highly Cited
2004
The Minimal Active Domain of Endostatin Is a Heparin-Binding Motif that Mediates Inhibition of Tumor Vascularization
Endostatin constitutes the COOH-terminal 20,000 Da proteolytic fragment of collagen XVIII and has been shown to possess… 
Highly Cited
2002
Highly Cited
2002
Prospective analysis of circulating endostatin levels in patients with renal cell carcinoma
The aim of the current study was to assess circulating levels of endogenous endostatin in patients with renal carinoma and to… 
Highly Cited
2002
Highly Cited
2002
Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma.
Endostatin, the 20-kDa C-terminal fragment of collagen XVIII, has previously been shown to inhibit growth and induce regression… 
Highly Cited
2002
Highly Cited
2002
Antiangiogenic activity of endostatin inhibits c6 glioma growth
Angiogenesis is a vital component of the development and progression of many human solid tumors. Glioblastoma multiforme is one… 
2002
2002
Targeting multiple biological pathways as a strategy to improve the treatment of cancer.
Over the past several years, the concept of targeted biological therapy for the treatment of cancer and other disease has emerged… 
Highly Cited
2001
Highly Cited
2001
Intra‐tumoral administration of naked plasmid DNA encoding mouse endostatin inhibits renal carcinoma growth
Endostatin is a C‐terminal fragment of collagen XVIII and has potent anti‐angiogenic and anti‐tumor activity. Mouse endostatin… 
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