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Receptors, Tumor Necrosis Factor, Type II

Known as: CD 120b Antigen, TNF-R2, CD120b Antigen 
A tumor necrosis factor receptor subtype that is expressed primarily in IMMUNE SYSTEM cells. It has specificity for membrane-bound form of TUMOR… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (2)

CD AntigensTumor Necrosis Factor Receptor
In BloodProcess of secretionTNFRSF1B geneTNFRSF1B wt Allele

Narrower (1)

TNFRSF1B protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
New Aspects of Lipotoxicity in Nonalcoholic Steatohepatitis
NASH is becoming increasingly common worldwide because of the growing global prevalence of obesity and consequently NAFLD… 
Highly Cited
2014
Highly Cited
2014
Transmembrane TNF-α Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2
It has been reported that TNFR2 is involved in regulatory T cell induction and myeloid-derived suppressor cell (MDSC… 
Highly Cited
2005
Highly Cited
2005
Posttranscriptional Downregulation of c-IAP2 by the Ubiquitin Protein Ligase c-IAP1 In Vivo
ABSTRACT Inhibitor of apoptosis proteins (IAPs) c-IAP1 and c-IAP2 were identified as part of the tumor necrosis factor receptor 2… 
Highly Cited
2005
Highly Cited
2005
TNF‐α induced c‐IAP1/TRAF2 complex translocation to a Ubc6‐containing compartment and TRAF2 ubiquitination
Signaling through tumor necrosis factor receptor 2 (TNF‐R2) results in ubiquitination of TRAF2 by the E3 c‐IAP1. In this report… 
Highly Cited
2003
Highly Cited
2003
Recruitment of TNF Receptor 1 to Lipid Rafts Is Essential for TNFα-Mediated NF-κB Activation
Highly Cited
2003
Highly Cited
2003
Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes.
CD8+CD25+ cells, which expressed high levels of Foxp3, glucocorticoid-induced tumor necrosis factor receptor (GITR), CCR8, tumor… 
Highly Cited
2003
Highly Cited
2003
The Role of Nuclear Factor κB in Tumor Necrosis Factor-Regulated Transcription of the Human μ-Opioid Receptor Gene
Opioids and their receptors are key players in a cross-talk between the nervous and immune systems. For example, the endogenous… 
Highly Cited
2002
Highly Cited
2002
Etk/Bmx as a Tumor Necrosis Factor Receptor Type 2-Specific Kinase: Role in Endothelial Cell Migration and Angiogenesis
ABSTRACT Tumor necrosis factor (TNF) is a cytokine that mediates many pathophysiologial processes, including angiogenesis… 
Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor α‐induced activation of c‐jun N‐terminal kinase is mediated by TRAF2
Tumor necrosis factor α (TNFα) a pro‐inflammatory cytokine is an endogenous mediator of septic shock, inflammation, anti‐viral… 
Highly Cited
1995
Highly Cited
1995
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells.
A rat/mouse T cell hybridoma (PC60) was transfected either with human (h) TNF-R p55 (TNF-R55), p75 (TNF-R75) or both cDNAs. hTNF… 
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