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Receptors, Proteinase-Activated

Known as: Receptors, Endopeptidase-Activated, Receptors, Protease-Activated, Endopeptidase-Activated Receptors 
A class of receptors that are activated by the action of PROTEINASES. The most notable examples are the THROMBIN RECEPTORS. The receptors contain… 
National Institutes of Health

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Papers overview

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2018
2018
Percutaneous Coronary Intervention: Adjunctive Pharmacology
Percutaneous coronary intervention (PCI) promotes thrombosis by inducing extreme vascular injury. The concomitant presence of… 
Review
2017
Review
2017
Multiple receptor-mediated functions of activated protein
The central effector protease of the protein C pathway, activated protein C (APC), interacts with the endothelial cell protein C… 
2013
2013
[Roles of protease-activated receptor-1 in thrombin-induced brain injury and neurogenesis in rats].
OBJECTIVE To investigate the roles of protease-activated receptors (PARs) in thrombin-induced brain injury and neurogenesis in… 
2009
2009
Isothermal titration calorimetry and inhibition of platelets aggregation by [D-Phe/(transcinnamoyl)-Pro-D-Arg-P1'-CONH2] peptides inhibitors of thrombin.
Introduction Thrombin is the major product of the plasma coagulation “cascade” of sequential “zymogen-to-protease” steps. As the… 
2008
2008
Kinin B 2 Receptor Mediates Induction of Cyclooxygenase-2 and Is Overexpressed in Head and Neck Squamous Cell Carcinomas
Bradykinin has been shown to promote growth and migration of head and neck squamous cell carcinoma (HNSCC) cells via epidermal… 
2005
2005
Recent advances in basic science CLINICAL RELEVANCE OF PROTEINASE ACTIVATED RECEPTORS ( PARS ) IN THE GUT N Vergnolle
Correspondence to: Dr N Vergnolle, Mucosal Inflammation Research Group, Department of Pharmacology and Therapeutics, Faculty of… 
2004
2004
Antithrombin extends its job
Endothelial cells are triggered by local coagulant conditions. They respond to the coagulation factors thrombin, factor Xa… 
2003
2003
Differential Ca 2 signaling by thrombin and protease-activated receptor-1-activating peptide in human brain microvascular endothelial cells
Kim, Yuri V., Francescopaolo Di Cello, Coryse S. Hillaire, and Kwang Sik Kim. Differential Ca signaling by thrombin and protease… 
2002
2002
A growing set of platelet-activating bacterial proteins.
We read with interest the paper by Lourbakos et al[1][1]that reports activation of platelets by the Porphyromonas gingivalis… 
2001
2001
Thrombin, thrombomodulin, and extracellular signal-regulated kinases regulating cellular proliferation.
Thrombin, a coagulation protease, is primarily known for its regulation of hemostasis and thrombosis. However, this enzyme also… 
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