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Human Decidual Natural Killer Cells Are a Unique NK Cell Subset with Immunomodulatory Potential
- L. Koopman, H. Kopcow, +8 authors J. Strominger
- Medicine, Biology
- The Journal of experimental medicine
- 20 October 2003
Natural killer cells constitute 50–90% of lymphocytes in human uterine decidua in early pregnancy. Here, CD56bright uterine decidual NK (dNK) cells were compared with the CD56bright and CD56dim… Expand
Inflammation and Pregnancy
- J. R. Challis, C. Lockwood, L. Myatt, J. Norman, J. Strauss, F. Petraglia
- Medicine, Computer Science
- Reproductive sciences
- 15 September 2006
Inflammation is a process by which tissues respond to various insults. It is characterized by upregulation of chemokines, cytokines, and pattern recognition receptors that sense microbes and tissue… Expand
Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery.
- C. Lockwood, A. Senyei, +6 authors T. Garite
- The New England journal of medicine
- 1 February 1992
BACKGROUND Preterm delivery is the leading cause of neonatal mortality in the United States, but efforts to address the problem are hampered by the inability to predict accurately which pregnancies… Expand
A novel immortalized human endometrial stromal cell line with normal progestational response.
Obtaining primary human endometrial stromal cells (HESCs) for in vitro studies is limited by the scarcity of adequate human material and the inability to passage these cells in culture for long… Expand
Pregnancy loss in the antiphospholipid-antibody syndrome--a possible thrombogenic mechanism.
BACKGROUND The mechanisms of vascular thrombosis and pregnancy loss in the antiphospholipid-antibody syndrome are unknown. Levels of annexin V, a phospholipid-binding protein with potent… Expand
Pregnancy Outcome and Weight Gain Recommendations for the Morbidly Obese Woman
- A. Bianco, S. Smilen, Y. Davis, S. Lopez, R. Lapinski, C. Lockwood
- Obstetrics and gynecology
- 1 January 1998
Objective To compare pregnancy outcomes between morbidly obese and nonobese women and to determine the effect of gestational weight gain on pregnancy outcome in morbidly obese women. Methods A… Expand
Inherited thrombophilias in pregnant patients: detection and treatment paradigm.
- C. Lockwood
- Obstetrics and gynecology
- 1 February 2002
Inherited thrombophilias are the leading cause of maternal thromboembolism and are associated with an increased risk of certain adverse pregnancy outcomes including second- and third-trimester fetal… Expand
Markers of risk for preterm delivery
Abstract Clinical and experimental evidence indicate that PTD results from four primary pathogenic mechanisms: activation of the maternal or fetal HPA axis; amniochorionic-decidual or systemic… Expand
American Thoracic Society documents: an official American Thoracic Society/Society of Thoracic Radiology Clinical Practice Guideline--Evaluation of Suspected Pulmonary Embolism in Pregnancy.
BACKGROUND Pulmonary embolism (PE) is a leading cause of maternal mortality in the developed world. Along with appropriate prophylaxis and therapy, prevention of death from PE in pregnancy requires a… Expand
Depression and Serotonin Reuptake Inhibitor Treatment as Risk Factors for Preterm Birth
Background: Major depressive disorder and the use of serotonin reuptake inhibitors (SRIs) in pregnancy have been associated with preterm birth. Studies that have attempted to separate effects of… Expand