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Human Decidual Natural Killer Cells Are a Unique NK Cell Subset with Immunomodulatory Potential
- L. Koopman, H. Kopcow, J. Strominger
- Biology, MedicineThe Journal of experimental medicine
- 20 October 2003
Natural killer cells constitute 50–90% of lymphocytes in human uterine decidua in early pregnancy and are compared with the CD56bright and CD56dim peripheral NK cell subsets by microarray analysis, with verification of results by flow cytometry and RT-PCR.
The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists.
Inflammation and Pregnancy
- J. Challis, C. Lockwood, L. Myatt, J. Norman, J. Strauss, F. Petraglia
- Biology, MedicineReproductive sciences
- 15 September 2006
During pregnancy, the balance of Th1 (cell-mediated immunity) and Th2 (humoral immunity) cytokines is characterized by an initial prevalence of Th2 cytokines, followed by a progressive shift toward Th1 predominance late in gestation, that when is abnormal, may initiate and intensify the cascade of inflammatory cytokine production involved in adverse pregnancy outcomes.
A novel immortalized human endometrial stromal cell line with normal progestational response.
An immortalized HESC line has been developed that is karyotypically, morphologically, and phenotypically similar to the primary parent cells, and it is a powerful and consistent resource for in vitro work.
Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery.
The presence of cervicovaginal fetal fibronectin in the second and third trimesters of pregnancy identifies a subgroup of women who are at high risk for preterm delivery.
Pregnancy Outcome and Weight Gain Recommendations for the Morbidly Obese Woman
Inherited thrombophilias in pregnant patients: detection and treatment paradigm.
- C. Lockwood
- Medicine, BiologyObstetrics and gynecology
- 1 February 2002
Assessment of fetal growth.
Impact of a comprehensive patient safety strategy on obstetric adverse events.
Markers of risk for preterm delivery
Abstract Clinical and experimental evidence indicate that PTD results from four primary pathogenic mechanisms: activation of the maternal or fetal HPA axis; amniochorionic-decidual or systemic…