Receptors, Complement 3d

Known as: CD21, Virus Receptor, Epstein-Barr, Complement 3d Receptors 
Molecular sites on or in B-lymphocytes, follicular dendritic cells, lymphoid cells, and epithelial cells that recognize and combine with COMPLEMENT… (More)
National Institutes of Health

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Broader (3)

Antigens, Differentiation, B-LymphocyteComplement ReceptorReceptors, Virus
CD AntigensCD21 Ag:PrThr:Pt:Tiss:Ord:Immune stainCR2 geneComplement C3d
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Narrower (1)

TT30 fusion protein, human

Papers overview

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Highly Cited
2002
Highly Cited
2002
Mice deficient in complement receptors 1 and 2 lack a tissue injury-inducing subset of the natural antibody repertoire.
Intestinal ischemia-reperfusion (IR) injury is initiated when natural Abs recognize neoantigens that are revealed on ischemic… (More)
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Review
2002
Review
2002
The dual function of the splenic marginal zone: essential for initiation of anti-TI-2 responses but also vital in the general first-line defense against blood-borne antigens.
The splenic marginal zone (S-MZ) is especially well equipped for rapid humoral responses and is unique in its ability to initiate… (More)
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Highly Cited
2001
Highly Cited
2001
Structure of complement receptor 2 in complex with its C3d ligand.
Complement receptor 2 (CR2/CD21) is an important receptor that amplifies B lymphocyte activation by bridging the innate and… (More)
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Review
2000
Review
2000
Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex.
The membrane protein complex CD19/CD21 couples the innate immune recognition of microbial antigens by the complement system to… (More)
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Highly Cited
1998
Highly Cited
1998
X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2.
Activation and covalent attachment of complement component C3 to pathogens is the key step in complement-mediated host defense… (More)
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Highly Cited
1998
Highly Cited
1998
Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response.
Two mechanisms could account for the impaired humoral immune response found in Cr2-/- mice. The absence of complement receptors 1… (More)
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Highly Cited
1996
Highly Cited
1996
Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2.
Complement receptor 1 (CR1, CD35) and complement receptor 2 (CR2, CD21) have been implicated as regulators of B-cell activation… (More)
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Highly Cited
1992
Highly Cited
1992
CD21 is a ligand for CD23 and regulates IgE production
THE molecule CD23, a low-affinity receptor for IgE (FcεR2)1,2, is a type II transmembrane molecule expressed on many haemopoietic… (More)
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Highly Cited
1990
Highly Cited
1990
In vivo inhibition of the antibody response by a complement receptor- specific monoclonal antibody
BALB/c mice were injected intravenously with three different monoclonal antibodies (mAbs) specific for complement receptor 1 (CR1… (More)
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Highly Cited
1982
Highly Cited
1982
Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.
The isolation from rabbit lung of a cofactor for thrombin-catalyzed Protein C activation is described. The lung is perfused to… (More)
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