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Association between active Wegener's granulomatosis and anticytoplasmic antibodies.
- J. Tervaert, F. J. van der Woude, +7 authors T. The
- Archives of internal medicine
- 1 November 1989
Autoantibodies reacting with the cytoplasm of granulocytes and monocytes (anticytoplasmic antibodies [ACPAs]) were found in 42 of 45 patients with active Wegener's granulomatosis (WG) (sensitivity,… Expand
Causes of death in cancer patients.
Causes of death in the year 1970 were analyzed retrospectively on the basis of clinical and pathologic reports of 506 cases in the Roswell Park Memorial Institute and Hospital. The single major cause… Expand
Immunologic aspects of renal disease.
The kidney can become involved in immune-mediated diseases through 3 mechanisms. It can be the primary target of antibody-mediated injury. Good-pasture syndrome, with antibodies directed at the… Expand
Hemorrheologic effects of metabolites of pentoxifylline (Trental).
Pentoxifylline (Trental) is metabolized by red blood cells and the liver into seven metabolites. Metabolites I and V have significant hemorrheologic effects. They are both similar to pentoxifylline… Expand
Myelodysplastic syndromes and autoimmune diseases--case series and review of literature.
Our objective was to recognize the association of autoimmune diseases (AD) in patients with myelodysplastic syndromes (MDS) and understand how this association could affect prognosis and management… Expand
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment.
Determination of anti-malignin antibody and malignin in 1,026 cancer patients and controls: relation of antibody to survival.
The antibody to Malignin. a cancer ceJJ 10.000 Dalton poly· peptide of known composition. was quantitath'ely determined Send Reprint Requests to : Dr. Samuel Bogoc:h. 46 East 915t Street. New York.… Expand
Intracellular signaling events associated with the induction of proliferation of normal human B lymphocytes by two different antigenically related human B cell growth factors (high molecular weight B…
- J. Ambrus, L. Chesky, +4 authors E. Brown
- Biology, Medicine
- The Journal of biological chemistry
- 25 February 1991
High molecular weight B cell growth factor (HMW-BCGF) and the complement component, Factor B, are antigenically related. HMW-BCGF and the physiologic Factor B activation fragment Bb, are both… Expand
Development of Autoimmunity in IL-14α-Transgenic Mice1
Multiple genetic loci contribute to the development of systemic lupus erythematosus (SLE). In murine models for SLE, various genes on chromosome four have been implicated. IL-14 is a cytokine… Expand