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Receptor Up-Regulation

Known as: receptor upregulation 
A positive regulatory process that increases ligand-receptor interactions. Increase in receptor binding after ligand exposure can result from… 
National Institutes of Health

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Broader (1)

Up-Regulation (Physiology)
receptor expression

Papers overview

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Highly Cited
2006
Highly Cited
2006
Neuronal Angiotensin II Type 1 Receptor Upregulation in Heart Failure: Activation of Activator Protein 1 and Jun N-Terminal Kinase
Chronic heart failure (CHF) is a leading cause of mortality in developed countries. Angiotensin II (Ang II) plays an important… 
2005
2005
The role of NMDA receptor upregulation in phencyclidine-induced cortical apoptosis in organotypic culture.
2005
2005
Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy.
BACKGROUND The podocyte is bathed in an angiotensin II (AngII)-rich ultrafiltrate, but the impact of AngII on podocyte… 
2003
2003
Upregulation of beta 1-adrenergic receptors in ovariectomized rat hearts.
Changes in cardiac myofilament Ca(2+) activation have been demonstrated in ovariectomized rats. The underlying mechanisms… 
Highly Cited
1998
Highly Cited
1998
Regulation of nicotinic receptors in the brain of mice withdrawn from chronic oral nicotine treatment
The effect of nicotine withdrawal on regional regulation of brain nicotinic receptors was studied in mice after chronic… 
Highly Cited
1998
Highly Cited
1998
Fas and Fas Ligand Expression on Human Peripheral Blood Leukocytes
Objectives: Study of Fas and Fas ligand (Fas-L) expression, as well as sFas-L release, by fresh human peripheral blood leukocytes… 
Highly Cited
1996
Highly Cited
1996
NMDA receptor upregulation: molecular studies in cultured mouse cortical neurons after chronic antagonist exposure
We examined the possibility of changes in gene expression of the NMDA receptor subunits after chronic antagonist treatment… 
1992
1992
Dopamine depletion produces augmented behavioral responses to a Mu‐, but not a delta‐opioid receptor agonist in the nucleus accumbens: Lack of a role for receptor upregulation
Microinjection of either m̈ ‐ or ð‐ opioid agonists into the nucleus accumbens produces an increased locomotor activity, and when… 
Highly Cited
1989
Highly Cited
1989
Chronic opioid antagonist treatment: assessment of receptor upregulation.
Highly Cited
1987
Highly Cited
1987
The murine lymphocyte receptor for IgE. IV. The mechanism of ligand-specific receptor upregulation on B cells.
Rodent B cells respond to culture with IgE by increasing their IgE-specific Fc receptors (Fc epsilon R). The mechanism of this… 
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