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Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
The First Key Symposium was held in Stockholm, Sweden, 2–5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild CognitiveExpand
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Neuronal nicotinic receptors in the human brain
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand gated ion channels which are widely distributed in the human brain. Multiple subtypes of these receptors exist, each withExpand
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Two-year follow-up of amyloid deposition in patients with Alzheimer's disease.
Beta amyloid is one of the major histopathological hallmarks of Alzheimer's disease. We recently reported in vivo imaging of amyloid in 16 Alzheimer patients, using the PET ligandExpand
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Spatial pattern of cerebral glucose metabolism (PET) correlates with localization of intracerebral EEG-generators in Alzheimer's disease
BACKGROUND Since the measurement of human cerebral glucose metabolism (GluM) by positron emission tomography (PET) and that of human cerebral electrical activity by EEG reflect synaptic activity,Expand
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Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.
IMPORTANCE Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in personsExpand
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  • PDF
Brain Activation in Young and Older Adults During Implicit and Explicit Retrieval
Positron emission tomography was used to study regional cerebral blood flow (H215O method) in groups of young and older adults during implicit and explicit retrieval, following a procedure devised byExpand
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Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment
The objective of this study was to assess whether reduced glucose metabolism (rCMRGlu) and cognitive functioning could predict development of Alzheimer's disease (AD) in subjects with mild cognitiveExpand
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Intracerebroventricular Infusion of Nerve Growth Factor in Three Patients with Alzheimer’s Disease
Nerve growth factor (NGF) is important for the survival and maintenance of central cholinergic neurons, a signalling system impaired in Alzheimer’s disease. We have treated 3 patients withExpand
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Cholinesterase Inhibitors in the Treatment of Alzheimer’s Disease
Cholinesterase inhibitors are currently the most established treatment strategy in Alzheimer’s disease. The treatment effect appears mainly to be symptomatic. Effects on progression of the diseaseExpand
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Amyloid imaging in Alzheimer's disease
  • A. Nordberg
  • Psychology, Medicine
  • Neuropsychologia
  • 1 May 2008
Alzheimer's disease (AD) is a complex neurodegenerative disorder of which the exact cause is still not known. There has, however, been remarkable progress in the understanding of theExpand
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