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Receptor-CD3 Complex, Antigen, T-Cell

Known as: Receptor-CD3 Complex, Antigen, T-Cell [Chemical/Ingredient], TCR-CD3, T Cell Antigen Receptor CD3 Complex 
Molecule composed of the non-covalent association of the T-cell antigen receptor (RECEPTORS, ANTIGEN, T-CELL) with the CD3 complex (ANTIGENS, CD3… 
National Institutes of Health

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In BloodSignal Transductionagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2014
Highly Cited
2014
Molecular architecture of the αβ T cell receptor–CD3 complex
Significance The T-cell receptor (TCR) does not signal on its own. Instead, it is constitutively associated with the CD3… 
Highly Cited
2002
Highly Cited
2002
TCR signal initiation machinery is pre‐assembled and activated in a subset of membrane rafts
Recent studies suggest that rafts are involved in numerous cell functions, including membrane traffic and signaling. Here we… 
Highly Cited
2001
Highly Cited
2001
Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells
NKG2D is an activating receptor that stimulates innate immune responses by natural killer cells upon engagement by MIC ligands… 
Highly Cited
2001
Highly Cited
2001
Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells.
NKG2D is an activating receptor that stimulates innate immune responses by natural killer cells upon engagement by MIC ligands… 
Highly Cited
1998
Highly Cited
1998
Nasal immune system: distinctive Th0 and Th1/Th2 type environments in murine nasal‐associated lymphoid tissues and nasal passage, respectively
The nasal mucosa, an important arm of the mucosal immune system, is the first site of contact with inhaled antigens to induce an… 
Highly Cited
1995
Highly Cited
1995
Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells
T-cell receptor (TCR) cross-linking increases tyrosine phosphorylation of multiple proteins, only a few of which have been… 
Highly Cited
1994
Highly Cited
1994
Partial T cell signaling: Altered phospho-ζ and lack of zap70 recruitment in APL-induced T cell anergy
Highly Cited
1993
Highly Cited
1993
Activation interferes with the APO-1 pathway in mature human T cells.
One of the mechanisms to terminate a specific immune response may involve elimination of antigen activated T cells by programmed… 
Review
1993
Review
1993
Distinct roles for CD4 and CD8 as co-receptors in antigen receptor signalling.
Highly Cited
1990
Highly Cited
1990
T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation.
Triggering of the antigen-specific T cell receptor-CD3 complex (TCR-CD3) stimulates a rapid phospholipase C-mediated hydrolysis… 
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