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Receptor, PAR-1

Known as: Receptor, PAR1, Receptor, PAR 1, Protease Activated Receptor 1 
A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms… 
National Institutes of Health

Related topics

Related topics

10 relations
F2R geneIn Bloodagonistsantagonists & inhibitors

Narrower (2)

PAR-1 receptor (1-41), humanProtease-Activated Receptor 1, human

Broader (1)

Thrombin Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Inhibition of Thrombin as a Novel Strategy in the Treatment of Scleroderma-Associated Interstitial Lung Disease
Activation of the coagulation cascade leading to generation of thrombin has been extensively documented in various forms of lung… 
2010
2010
Phosphoinositide 3-kinase induced activation and cytoskeletal translocation of protein kinase CK2 in protease activated receptor 1-stimulated platelets
2010
2010
Ligand binding and ectodomain shedding of the mannose 6-phosphate/insulin-like growth factor II receptor
2009
2009
The role of platelet thrombin receptors PAR1 and PAR4 in platelet activation
Platelets play a pivotal role in coagulation and haemostasis. Their most prominent task is to seal damaged blood vessels by the… 
2007
2007
Distinct Ca 2+ requirement for NO production between proteinase-activated receptor 1 and 4 (PAR 1 and PAR 4 ) in vascular endothelial cells *
Proteinase-activated receptor 1 and 4 (PAR 1 and PAR 4 ) are the major receptors mediating thrombin-induced NO production in… 
2005
2005
CHANGES IN THE CONCENTRATION OF FLUORIDE AND BIOGENIC ELEMENTS IN THE SERUM AND BONES OF FEMALE RATS WITH STREPTOZOTOCIN-INDUCED DIABETES
The aim of this study was to determine if streptozotocin-induced diabetes in rats as a model for Type-1 human diabetes causes… 
2005
2005
[Human lung epithelial cells produce interleukin-8 through protease-activated receptor 1].
OBJECTIVE To investigate the actions of protease-activated receptor 1 (PAR1) agonists and thrombin on the secretion of… 
2004
2004
Diagnostics and therapeutics for diseases associated with g-protein coupled protease activated receptor 1 (par1)
  • 2004
  • Corpus ID: 116850062
1999
1999
Time course of recovery of endothelial cell surface thrombin receptor (PAR-1) expression.
We studied dynamics of cell surface expression of proteolytically activated thrombin receptor (PAR-1) in human pulmonary artery… 
1996
1996
Erratum: The insulin-like growth factor II receptor gene is a target of microsatellite instability in human gastrointestinal tumours (Nature Genetics (1996) 14 (255-257))