Receptor, PAR-1

Known as: Receptor, PAR1, Receptor, PAR 1, Protease Activated Receptor 1 
A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Protease-activated receptor 1 (PAR1) is the prototypical member of a family of G-protein-coupled receptors that mediate cellular… (More)
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Highly Cited
2011
Highly Cited
2011
A pathogenic role for high-mobility group box 1 (HMGB1) protein has been postulated in severe sepsis. Activated protein C (APC… (More)
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Highly Cited
2007
Highly Cited
2007
Highly Cited
2007
Ever-increasing evidence in the literature suggests that the antiinflammatory and cytoprotective properties of activated protein… (More)
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Highly Cited
2006
Highly Cited
2006
Activation of latent TGF-beta by the alpha(v)beta6 integrin is a critical step in the development of acute lung injury. However… (More)
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Highly Cited
2004
Highly Cited
2004
Activated protein C (APC), a serine protease with anticoagulant and anti-inflammatory activities, exerts direct cytoprotective… (More)
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Highly Cited
2001
Highly Cited
2001
Cell signaling by coagulation factor Xa (Xa) contributes to pro-inflammatory responses in vivo. This study characterizes the… (More)
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Highly Cited
1998
Highly Cited
1998
Thrombin is a multifunctional serine protease that has a crucial role in blood coagulation. It is also a potent mesenchymal cell… (More)
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Highly Cited
1987
Highly Cited
1987
The primary structure of human insulin-like growth factor II receptor, predicted from the complementary DNA sequence, reveals a… (More)
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