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Receptor, Notch1

Known as: Notch1 Protein, Notch1 Receptor, Receptor, Notch1 [Chemical/Ingredient] 
A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The mechanisms by which transcription factor haploinsufficiency alters the epigenetic and transcriptional landscape in human… Expand
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Highly Cited
2014
Highly Cited
2014
Significance Triple-negative breast cancers comprise 10% of invasive breast carcinomas but are responsible for a disproportionate… Expand
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Highly Cited
2014
Highly Cited
2014
Human breast cancers include cancer stem cell populations as well as nontumorigenic cancer cells. Breast cancer stem cells have… Expand
Highly Cited
2012
Highly Cited
2012
Uterine receptivity implies a dialogue between the hormonally primed maternal endometrium and the free‐floating blastocyst… Expand
Highly Cited
2006
Highly Cited
2006
The bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, occurring in 1-2% of the population. In a… Expand
Highly Cited
2006
Highly Cited
2006
The role of NOTCH1 as an oncogene or tumor suppressor appears to be cell type-specific. Medullary thyroid cancer (MTC) cells… Expand
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Highly Cited
2003
Highly Cited
2003
The cell fate determinant Numb influences developmental decisions by antagonizing the Notch signaling pathway. However, the… Expand
Highly Cited
1998
Highly Cited
1998
The Notch intracellular region (RAMIC) interacts with a DNA binding protein RBP-J to activate transcription of genes that inhibit… Expand
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Highly Cited
1997
Highly Cited
1997
The Notch genes of Drosophila melanogaster and vertebrates encode transmembrane receptors that help determine cell fate during… Expand
Highly Cited
1997
Highly Cited
1997
Signaling through Notch receptors has been implicated in the control of cellular differentiation in animals ranging from… Expand