Receptor, Notch1

Known as: Notch1 Protein, Notch1 Receptor, Receptor, Notch1 [Chemical/Ingredient] 
A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The mechanisms by which transcription factor haploinsufficiency alters the epigenetic and transcriptional landscape in human… (More)
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Highly Cited
2014
Highly Cited
2014
Breast cancer is the second-leading cause of cancer-related deaths in women, but the details of how it begins remain elusive… (More)
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2014
2014
Human breast cancers include cancer stem cell populations as well as nontumorigenic cancer cells. Breast cancer stem cells have… (More)
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Highly Cited
2006
Highly Cited
2006
The bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, occurring in 1-2% of the population. In a… (More)
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Highly Cited
2006
Highly Cited
2006
The role of NOTCH1 as an oncogene or tumor suppressor appears to be cell type-specific. Medullary thyroid cancer (MTC) cells… (More)
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Highly Cited
2003
Highly Cited
2003
The cell fate determinant Numb influences developmental decisions by antagonizing the Notch signaling pathway. However, the… (More)
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Highly Cited
1998
Highly Cited
1998
The Notch intracellular region (RAMIC) interacts with a DNA binding protein RBP-J to activate transcription of genes that inhibit… (More)
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Highly Cited
1997
Highly Cited
1997
Signaling through Notch receptors has been implicated in the control of cellular differentiation in animals ranging from… (More)
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Highly Cited
1997
Highly Cited
1997
The Notch genes of Drosophila melanogaster and vertebrates encode transmembrane receptors that help determine cell fate during… (More)
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Highly Cited
1996
Highly Cited
1996
The Notch gene family encodes transmembrane proteins that have been implicated in control of diverse cellular differentiation… (More)
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