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Receptor, Angiotensin, Type 1

Known as: Angiotensin Type 1 Receptor, Angiotensin II Type 1 Receptor, Receptor, Angiotensin AT1 
An angiotensin receptor subtype that is expressed at high levels in a variety of adult tissues including the CARDIOVASCULAR SYSTEM, the KIDNEY, the… 
National Institutes of Health

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Receptor, Angiotensin, Type 1aReceptor, Angiotensin, Type 1b

Papers overview

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Highly Cited
2014
Highly Cited
2014
Endothelial constitutive nitric oxide synthase, angiotensin converting enzyme, angiotensin II type 1 receptor gene polymorphisms and endothelial functions in healthy individuals.
INTRODUCTION Endothelial dysfunction is recognized as an early and initiating event in the pathogenesis of coronary artery… 
Highly Cited
2013
Highly Cited
2013
The apelin receptor inhibits the angiotensin II type 1 receptor via allosteric trans‐inhibition
The apelin receptor (APJ) is often co‐expressed with the angiotensin II type‐1 receptor (AT1) and acts as an endogenous counter… 
Highly Cited
2010
Highly Cited
2010
Anti-Angiotensin Type 1 Receptor Antibodies Associated With Antibody Mediated Rejection in Donor HLA Antibody Negative Patients
Background. Angiotensin type 1 receptor (AT1R) mediates most physiologic and pathophysiologic actions of its endogenous ligand… 
Review
2008
Review
2008
AT2 receptors: Functional relevance in cardiovascular disease
Highly Cited
2007
Highly Cited
2007
Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra
BackgroundRecent attention has focused on understanding the role of the brain-renin-angiotensin-system (RAS) in stroke and… 
Highly Cited
2002
Highly Cited
2002
Antithrombotic Effect of Captopril and Losartan Is Mediated by Angiotensin-(1-7)
Abstract—It is well established that renin-angiotensin system blockers exert NO/prostacyclin-dependent antithrombotic effects… 
Highly Cited
2002
Highly Cited
2002
In Vivo klotho Gene Transfer Ameliorates Angiotensin II-Induced Renal Damage
The klotho gene, originally identified by insertional mutagenesis in mice, suppresses the expression of multiple aging-associated… 
Highly Cited
1999
Highly Cited
1999
Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor activation.
Cross talk between oxidized LDL (ox-LDL) and angiotensin II (Ang II) may be relevant in atherosclerosis. In this study, we… 
Highly Cited
1998
Highly Cited
1998
Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide.
Nitric oxide (NO) plays an important role not only in the regulation of blood vessel tone, but also in the growth of vascular… 
Highly Cited
1996
Highly Cited
1996
Influence of angiotensin-converting enzyme and angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients.
BACKGROUND Clinical and experimental studies have demonstrated a major role of the renin-angiotensin system in the functional and… 
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