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Receptor, Angiotensin, Type 1a

Known as: Angiotensin II Type 1a Receptor, Angiotensin AT1a Receptor, Receptor, Angiotensin II Type 1a 
A subtype of angiotensin receptor found primarily in rodent species that have two type 1 angiotensin receptor genes.
National Institutes of Health

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Receptor, Angiotensin, Type 1

Papers overview

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Highly Cited
2006
Highly Cited
2006
Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice.
Blockade of the renin-angiotensin system slows the progression of diabetic nephropathy but fails to abolish the development of… Expand
Highly Cited
2005
Highly Cited
2005
Angiotensin-converting enzyme 2 protects from severe acute lung failure
Acute respiratory distress syndrome (ARDS), the most severe form of acute lung injury, is a devastating clinical syndrome with a… Expand
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Highly Cited
2005
Highly Cited
2005
Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice.
BACKGROUND/AIMS Pharmacological blockade of the renin-angiotensin system (RAS) attenuates liver fibrogenesis in rats. Here, we… Expand
Highly Cited
2002
Highly Cited
2002
β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation*
β-Arrestins are cytosolic proteins that mediate homologous desensitization of G protein-coupled receptors (GPCRs) by binding to… Expand
Highly Cited
2002
Highly Cited
2002
Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells*
Regulators of G protein signaling (RGS) proteins compose a highly diverse protein family best known for inhibition of G protein… Expand
Highly Cited
2001
Highly Cited
2001
Renal interstitial fibrosis is reduced in angiotensin II type 1a receptor-deficient mice.
Unilateral ureteral obstruction (UUO) results in tubulointerstitial fibrosis of the affected kidney by stimulating the renin… Expand
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Highly Cited
1999
Highly Cited
1999
Angiotensin II type 1A receptor knockout mice display less left ventricular remodeling and improved survival after myocardial infarction.
BACKGROUND Angiotensin II (Ang II) has been implicated in ventricular remodeling after myocardial infarction (MI), which is an… Expand
Highly Cited
1998
Highly Cited
1998
Angiotensin II type 1a receptor is involved in the occurrence of reperfusion arrhythmias.
BACKGROUND A growing body of evidence has suggested that the renin-angiotensin system plays an important role in the development… Expand
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Highly Cited
1996
Highly Cited
1996
Phosphorylation of the Type 1A Angiotensin II Receptor by G Protein-coupled Receptor Kinases and Protein Kinase C*
The type 1A angiotensin II receptor (AT1A-R), which mediates cardiovascular effects of angiotensin II, has been shown to undergo… Expand
Highly Cited
1995
Highly Cited
1995
Angiotensin II Type 1a Receptor-deficient Mice with Hypotension and Hyperreninemia (*)
Angiotensin (AT) II, the bioactive octapeptide in the renin-angiotensin system that plays a key role in cardiovascular… Expand
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