Receptor, Angiotensin, Type 1a
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Blockade of the renin-angiotensin system slows the progression of diabetic nephropathy but fails to abolish the development of… Expand Acute respiratory distress syndrome (ARDS), the most severe form of acute lung injury, is a devastating clinical syndrome with a… Expand BACKGROUND/AIMS
Pharmacological blockade of the renin-angiotensin system (RAS) attenuates liver fibrogenesis in rats. Here, we… Expand β-Arrestins are cytosolic proteins that mediate homologous desensitization of G protein-coupled receptors (GPCRs) by binding to… Expand Regulators of G protein signaling (RGS) proteins compose a highly diverse protein family best known for inhibition of G protein… Expand Unilateral ureteral obstruction (UUO) results in tubulointerstitial fibrosis of the affected kidney by stimulating the renin… Expand BACKGROUND
Angiotensin II (Ang II) has been implicated in ventricular remodeling after myocardial infarction (MI), which is an… Expand BACKGROUND
A growing body of evidence has suggested that the renin-angiotensin system plays an important role in the development… Expand The type 1A angiotensin II receptor (AT1A-R), which mediates cardiovascular effects of angiotensin II, has been shown to undergo… Expand Angiotensin (AT) II, the bioactive octapeptide in the renin-angiotensin system that plays a key role in cardiovascular… Expand