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Ras Signaling Pathway

Ras activates many signaling cascades. Here we illustrate some of the well-characterized cascades in a generic compilation of effector molecules. The… Expand
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Background: 8-Oxo-7,8-dihydroguanine (8-oxoG) is an abundant DNA base lesion repaired by 8-oxoguanine glycosylase (OGG1) via the… Expand
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Review
2006
Review
2006
The Ras signaling pathway controls important cellular responses to growth factors, and somatic mutations in RAS genes and other… Expand
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2004
2004
ATP-sensitive potassium (K(ATP)) channels regulate insulin release, vascular tone, and neuronal excitability. Whether these… Expand
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2003
2003
Connexin 43 (Cx43) is essential for survival and is tightly regulated at the transcriptional and post-transcriptional levels. A… Expand
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Highly Cited
1999
Highly Cited
1999
Components of the ras signaling pathway contribute to activation of cellular p53. In MCF-7 cells, p38 kinase activated p53 more… Expand
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1995
1995
Drosophila seven-up is an orphan receptor of the steroid receptor family that is required to specify photoreceptor neuron… Expand
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Highly Cited
1994
Highly Cited
1994
Activation of growth factor receptors results in tyrosine autophosphorylation and recruitment of SH2 domain-containing effectors… Expand
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Highly Cited
1994
Highly Cited
1994
The Caenorhabditis elegans locus lin-15 negatively regulates an intercellular signaling process that induces formation of the… Expand
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Highly Cited
1994
Highly Cited
1994
UV irradiation of mammalian cells activates AP-1 through a Ras-dependent pathway, independently of DNA damage. We show that the… Expand
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1994
1994
Activation of monocytes by bacterial lipopolysaccharides (LPSs) is a central component in the pathogenesis of septic shock… Expand
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