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Ras Signaling Pathway
Ras activates many signaling cascades. Here we illustrate some of the well-characterized cascades in a generic compilation of effector molecules. The…
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National Institutes of Health
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43 relations
AKT1 wt Allele
BAD wt Allele
BCL-XL Protein
BCL2L1 wt Allele
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Effect of corticision on orthodontic tooth movement in a rat model as assessed by RNA sequencing
Qi Gu
,
Shuyu Guo
,
+4 authors
Junqing Ma
Journal of Molecular Histology
2017
Corpus ID: 17251878
Corticision is a common technique to accelerate orthodontic tooth movement; however, not much is known about the underlying…
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Highly Cited
2012
Highly Cited
2012
Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-Oxoguanine*
I. Boldogh
,
G. Hajas
,
+6 authors
S. Mitra
Journal of Biological Chemistry
2012
Corpus ID: 205289364
Background: 8-Oxo-7,8-dihydroguanine (8-oxoG) is an abundant DNA base lesion repaired by 8-oxoguanine glycosylase (OGG1) via the…
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Highly Cited
2004
Highly Cited
2004
NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection.
Yu-Fung Lin
,
K. Raab-Graham
,
Y. Jan
,
L. Jan
Proceedings of the National Academy of Sciences…
2004
Corpus ID: 9600819
ATP-sensitive potassium (K(ATP)) channels regulate insulin release, vascular tone, and neuronal excitability. Whether these…
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Highly Cited
2003
Highly Cited
2003
Unexpected induction of the human connexin 43 promoter by the ras signaling pathway is mediated by a novel putative promoter sequence.
G. D. Carystinos
,
M. Kandouz
,
M. Alaoui-Jamali
,
G. Batist
Molecular Pharmacology
2003
Corpus ID: 22301613
Connexin 43 (Cx43) is essential for survival and is tightly regulated at the transcriptional and post-transcriptional levels. A…
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Highly Cited
1999
Highly Cited
1999
Phosphorylation of human p53 by p38 kinase coordinates N‐terminal phosphorylation and apoptosis in response to UV radiation
D. Bulavin
,
Shinichi Saito
,
+4 authors
A. Fornace
EMBO Journal
1999
Corpus ID: 8923076
Components of the ras signaling pathway contribute to activation of cellular p53. In MCF‐7 cells, p38 kinase activated p53 more…
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Highly Cited
1996
Highly Cited
1996
Effects of tyrosine kinase inhibitors on the proliferation of human breast cancer cell lines and proteins important in the RAS signaling pathway
Jeffrey W. Clark
,
A. Santos-Moore
,
L. E. Stevenson
,
A. Frackelton
International Journal of Cancer
1996
Corpus ID: 31420015
Breast cancers frequently over‐express a number of growth factor receptors. In addition, elevated src family kinase activity is…
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Highly Cited
1995
Highly Cited
1995
Cell fate control in the Drosophila retina by the orphan receptor seven-up: its role in the decisions mediated by the ras signaling pathway.
S. Kramer
,
S. West
,
Y. Hiromi
Development
1995
Corpus ID: 12962397
Drosophila seven-up is an orphan receptor of the steroid receptor family that is required to specify photoreceptor neuron…
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Highly Cited
1994
Highly Cited
1994
The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins.
S. G. Clark
,
X. Lu
,
H. Horvitz
Genetics
1994
Corpus ID: 17149235
Highly Cited
1994
Highly Cited
1994
Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway
A. Aronheim
,
D. Engelberg
,
Nanxin Li
,
N. Al-Alawi
,
J. Schlessinger
,
M. Karin
Cell
1994
Corpus ID: 23755496
Highly Cited
1994
Highly Cited
1994
Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the Ras signaling pathway.
Y. Geng
,
E. Gulbins
,
A. Altman
,
M. Lotz
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 9744651
Activation of monocytes by bacterial lipopolysaccharides (LPSs) is a central component in the pathogenesis of septic shock…
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