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Ras Signaling Pathway

Ras activates many signaling cascades. Here we illustrate some of the well-characterized cascades in a generic compilation of effector molecules. The… 
National Institutes of Health

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AKT1 wt AlleleBAD wt AlleleBCL-XL ProteinBCL2L1 wt Allele

Papers overview

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2017
2017
Effect of corticision on orthodontic tooth movement in a rat model as assessed by RNA sequencing
Corticision is a common technique to accelerate orthodontic tooth movement; however, not much is known about the underlying… 
2012
2012
Activation of Ras GTPases by OGG 1 complexed with 8-oxoG 1 SUPPLEMENTAL DATA Activation of Ras Signaling by the 8-oxoguanine DNA glycosylase Bound to Its Excision Product 8-oxoguanine
2009
2009
K-ras expression--marker of dysplasia and cancer.
Molecular and epidemiological data indicated that the presence of HPV virus is not sufficient to induce transformation… 
2004
2004
Ras activation is associated with Vitamin D receptor mRNA instability in HC11 mammary cells
Review
2002
Review
2002
Agents targeting ras signaling pathway.
Ras genes encode proteins that activate in an intracellular signaling network controlling differentiation, proliferation and cell… 
2002
2002
Basic fibroblast growth factor mediated growth inhibition in breast cancer cells is independent of ras signaling pathway.
Our previous studies have demonstrated that basic fibroblast growth factor (bFGF) inhibits the growth of MCF-7 human breast… 
1997
1997
Regulation of cellular response to cisplatin-induced DNA damage and DNA repair in cells overexpressing p185erbB-2 is dependent on the ras signaling pathway
We have examined the role of erbB-2 expression in the modulation of cellular toxicity to cisplatin. We have demonstrated that… 
1997
1997
Chromosomal mapping of five highly conserved murine homologues of the Drosophila RING finger gene seven-in-absentia.
Seven-in-absentia (sina) is epistatic to all other known genes in the sevenless-ras signaling pathway, which mediates R7… 
1995
1995
Insulin-dependent Tyrosine Phosphorylation of the vav Proto-oncogene Product in Cells of Hematopoietic Origin (*)
Insulin activates the ras signaling pathway and promotes hematopoietic cell proliferation. One possible mediator in such… 
1992
1992
Differences in GTPase-activating protein activity between liver tumors and normal liver tissue in mice.
The intrinsic GTPase activity of the cellular protein p21ras is strongly increased by two cytosolic proteins, the GTPase… 
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