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Radioligand Assay
Known as:
Radioreceptor Assays
, Protein-Binding Radioassay
, Assays, Radioreceptor
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Quantitative determination of receptor (binding) proteins in body fluids or tissue using radioactively labeled binding reagents (e.g., antibodies…
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National Institutes of Health
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Related topics
Related topics
7 relations
Immunoradiometric Assays
Ligands
Pharmacokinetic study
Protein Binding
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
In Vivo Imaging of Amyloid Deposition in Alzheimer Disease Using the Radioligand 18F-AV-45 (Flobetapir F 18)
D. Wong
,
P. Rosenberg
,
+13 authors
M. Pontecorvo
Journal of Nuclear Medicine
2010
Corpus ID: 933468
An 18F-labeled PET amyloid-β (Aβ) imaging agent could facilitate the clinical evaluation of late-life cognitive impairment by…
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Review
1995
Review
1995
Insulin-like Growth Factors and Cancer
D. Leroith
,
R. Baserga
,
L. Helman
,
Charles T. ROBERTS, Jr.
Annals of Internal Medicine
1995
Corpus ID: 7495177
Dr. Derek LeRoith (Molecular and Cellular Physiology Section, National Institute of Diabetes and Digestive and Kidney Diseases…
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Highly Cited
1994
Highly Cited
1994
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders.
Lloyd Paul Aiello
,
Robert L. Avery
,
+7 authors
John Edward Park
New England Journal of Medicine
1994
Corpus ID: 24659418
BACKGROUND Retinal ischemia induces intraocular neovascularization, which often leads to glaucoma, vitreous hemorrhage, and…
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Highly Cited
1991
Highly Cited
1991
Advanced glycosylation end products in patients with diabetic nephropathy.
Z. Makita
,
S. Radoff
,
+6 authors
H. Vlassara
New England Journal of Medicine
1991
Corpus ID: 27894901
BACKGROUND Glucose reacts nonenzymatically with proteins in vivo, chemically forming covalently attached glucose-addition…
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Highly Cited
1988
Highly Cited
1988
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium
R. Lyons
,
J. Keski‐oja
,
H. Moses
Journal of Cell Biology
1988
Corpus ID: 7867238
Transforming growth factor-beta (TGF beta) is produced by most cultured cells in an inactive form. Potential activation…
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Highly Cited
1986
Highly Cited
1986
Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose.
P. Hauschka
,
A. Mavrakos
,
M. Iafrati
,
S. Doleman
,
M. Klagsbrun
Journal of Biological Chemistry
1986
Corpus ID: 10163861
Highly Cited
1980
Highly Cited
1980
Ligand: a versatile computerized approach for characterization of ligand-binding systems.
P. Munson
,
D. Rodbard
Analytical Biochemistry
1980
Corpus ID: 30586550
Highly Cited
1980
Highly Cited
1980
Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanol-extracted serum.
William H. Daughaday
,
I. Mariz
,
Sandra L. Blethen
Journal of Clinical Endocrinology and Metabolism
1980
Corpus ID: 1085767
No agreement exists concerning the necessity for extracting serum somatomedin (Sm) before radioreceptor assay (RRA) and RIA. We…
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Highly Cited
1978
Highly Cited
1978
Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells.
J. Schlessinger
,
Y. Shechter
,
M. Willingham
,
I. Pastan
Proceedings of the National Academy of Sciences…
1978
Corpus ID: 23219572
We have studied in detail the binding of fluorescent derivatives of insulin and epidermal growth factor to 3T3 fibroblasts. We…
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Highly Cited
1967
Highly Cited
1967
Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay.
B. Murphy
Journal of Clinical Endocrinology and Metabolism
1967
Corpus ID: 36997085
ABSTRACT A method utilizing the steroid-binding properties of corticosteroid-binding globulin (CBG, transcortin) was described in…
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