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Pharmacokinetic study
Known as:
PHARMACOKINETIC
, PK Study
, pharmacokinetic studies
A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body.
National Institutes of Health
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Related topics
Related topics
3 relations
CDISC SDTM Trial Type Terminology
Clinical Data Interchange Standards Consortium Terminology
Radioligand Assay
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study
X. Mariette
,
F. Förger
,
+10 authors
E. Chakravarty
Annals of the Rheumatic Diseases
2017
Corpus ID: 4400187
Objectives There is a need for effective and safe treatment during pregnancy in women with chronic inflammatory diseases. This…
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Highly Cited
2016
Highly Cited
2016
A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine.
M. Cottrell
,
Kuo Yang
,
+11 authors
A. Kashuba
Journal of Infectious Diseases
2016
Corpus ID: 418805
BACKGROUND A novel translational pharmacology investigation was conducted by combining an in vitro efficacy target with mucosal…
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Highly Cited
2016
Highly Cited
2016
Ozanimod (RPC1063) is a potent sphingosine‐1‐phosphate receptor‐1 (S1P1) and receptor‐5 (S1P5) agonist with autoimmune disease‐modifying activity
F. Scott
,
B. Clemons
,
+10 authors
R. Peach
British Journal of Pharmacology
2016
Corpus ID: 5130415
Sphingosine1‐phosphate (S1P) receptors mediate multiple events including lymphocyte trafficking, cardiac function, and…
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Review
2013
Review
2013
Bioanalytical LC-MS/MS of protein-based biopharmaceuticals.
I. van den Broek
,
W. Niessen
,
W. V. van Dongen
Journal of chromatography. B, Analytical…
2013
Corpus ID: 11028540
Review
2008
Review
2008
The pharmacology of PEGylation: balancing PD with PK to generate novel therapeutics.
C. Fishburn
Journal of Pharmacy and Science
2008
Corpus ID: 13613516
Conjugation of macromolecules to polyethylene glycol (PEG) has emerged recently as an effective strategy to alter the…
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Highly Cited
2008
Highly Cited
2008
Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors.
A. O’Donnell
,
S. Faivre
,
+11 authors
I. Judson
Journal of Clinical Oncology
2008
Corpus ID: 39439335
PURPOSE To identify the optimal regimen and dosage of the oral mammalian target of rapamycin inhibitor everolimus (RAD001…
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Highly Cited
2008
Highly Cited
2008
BMC Clinical Pharmacology BioMed Central
2008
Corpus ID: 8597553
Highly Cited
2002
Highly Cited
2002
The pharmacokinetic-pharmacodynamic relationship for total and free mycophenolic Acid in pediatric renal transplant recipients: a report of the german study group on mycophenolate mofetil therapy.
L. Weber
,
M. Shipkova
,
+6 authors
B. Tönshoff
Journal of the American Society of Nephrology
2002
Corpus ID: 5663505
It is currently being debated whether pharmacokinetic monitoring of mycophenolic acid (MPA), the active constituent of…
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Review
2002
Review
2002
Dosing strategies for anticancer drugs: the good, the bad and body-surface area.
A. Felici
,
J. Verweij
,
A. Sparreboom
European Journal of Cancer
2002
Corpus ID: 23252827
Review
2001
Review
2001
Lipophilicity in PK design: methyl, ethyl, futile
H. Waterbeemd
,
Dennis A. Smith
,
B. Jones
J. Comput. Aided Mol. Des.
2001
Corpus ID: 8637486
Lipophilicity, often expressed as distribution coefficients (log D) in octanol/water, is an important physicochemical parameter…
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