Pharmacokinetic study

Known as: PHARMACOKINETIC, PK Study, pharmacokinetic studies 
A study of the process by which a drug is absorbed, distributed, metabolized, and eliminated by the body.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
With increasing clinical emergence of multidrug-resistant Gram-negative pathogens and the paucity of new agents to combat these… (More)
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Highly Cited
2010
Highly Cited
2010
This study presents PKSolver, a freely available menu-driven add-in program for Microsoft Excel written in Visual Basic for… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE To assess the feasibility of administering XRP6258, a new taxane with a low affinity for the multidrug resistance 1… (More)
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Highly Cited
2009
Highly Cited
2009
We previously reported interim results of a phase 1 trial in patients with chronic lymphocytic leukemia (CLL) whereby… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To identify the optimal regimen and dosage of the oral mammalian target of rapamycin inhibitor everolimus (RAD001… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Ranibizumab (rhuFab V2; Lucentis, Genentech, South San Francisco, CA) is a humanized monoclonal antibody fragment… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The objective of this study was to define the maximum-tolerated dose (MTD), the recommended phase II dose, the dose… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE To evaluate the basic pharmacokinetic (PK) characteristics of imatinib mesylate and assess the relationship between the… (More)
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Highly Cited
2003
Highly Cited
2003
Limited information exists on the pharmacokinetic (PK)-pharmacodynamic (PD) relationships of drugs against Mycobacterium… (More)
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Highly Cited
2001
Highly Cited
2001
Drugs that bind with high affinity and to a significant extent (relative to dose) to a pharmacologic target such as an enzyme… (More)
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