Rad30 protein

The encounter of replication forks with DNA lesions may lead to fork arrest and/or the formation of single-stranded gaps. A major… Expand

When a replicative DNA polymerase (Pol) is stalled by damaged DNA, a "polymerase switch" recruits specialized translesion… Expand

Human DNA polymerase eta (Pol eta) modulates susceptibility to skin cancer by promoting translesion DNA synthesis (TLS) past… Expand

DNA polymerases play a central role during homologous recombination (HR), but the identity of the enzyme(s) implicated remains… Expand

Stalled replication forks pose a serious threat to genome integrity. To overcome the catastrophic consequences associated with… Expand

Chicken B lymphocyte precursors and DT40 cells diversify their immunoglobulin-variable (IgV) genes through homologous… Expand

Most types of DNA damage block replication fork progression during DNA synthesis because replicative DNA polymerases are unable… Expand

Polkappa is one of many DNA polymerases involved in translesion DNA synthesis (TLS). It belongs to the Y-family of polymerases… Expand

Replication across unrepaired DNA lesions in mammalian cells is effected primarily by specialized, low fidelity DNA polymerases… Expand

The RAD30 gene of the yeast Saccharomyces cerevisiae is required for the error-free postreplicational repair of DNA that has been… Expand