Rad30 protein

When a replicative DNA polymerase (Pol) is stalled by damaged DNA, a “polymerase switch” recruits specialized translesion… Expand

ABSTRACT DNA polymerases play a central role during homologous recombination (HR), but the identity of the enzyme(s) implicated… Expand

Stalled replication forks pose a serious threat to genome integrity. To overcome the catastrophic consequences associated with… Expand

Chicken B lymphocyte precursors and DT40 cells diversify their immunoglobulin-variable (IgV) genes through homologous… Expand

Most types of DNA damage block replication fork progression during DNA synthesis because replicative DNA polymerases are unable… Expand

ABSTRACT The Rad6-Rad18 ubiquitin-conjugating enzyme complex of Saccharomyces cerevisiae promotes replication through DNA lesions… Expand

Polκ is one of many DNA polymerases involved in translesion DNA synthesis (TLS). It belongs to the Y‐family of polymerases along… Expand

Abasic (AP) sites are one of the most frequently formed lesions in DNA, and they present a strong block to continued synthesis by… Expand

In both yeast and humans, DNA polymerase (Pol) eta functions in error-free replication of ultraviolet-damaged DNA, and Poleta… Expand

The RAD30 gene of the yeast Saccharomyces cerevisiae is required for the error-free postreplicational repair of DNA that has been… Expand