RYR1 gene

Known as: PPP1R137, protein phosphatase 1, regulatory subunit 137, RYR1 
 
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
We have applied an optical super-resolution technique based on single-molecule localization to examine the peripheral… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVES We sought to investigate the effect of dantrolene, a drug generally used to treat malignant hyperthermia, on the Ca2… (More)
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Highly Cited
2007
Highly Cited
2007
cAMP is a powerful second messenger whose known general effector is protein kinase A (PKA). The identification of a cAMP binding… (More)
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Highly Cited
2006
Highly Cited
2006
Previous studies in transgenic mice and with isolated ryanodine receptors (RyR) have indicated that Ca2+-calmodulin-dependent… (More)
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Highly Cited
2006
Highly Cited
2006
The predominant cardiac Ca2+/calmodulin-dependent protein kinase (CaMK) is CaMKIIdelta. Here we acutely overexpress CaMKIIdeltaC… (More)
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Highly Cited
2004
Highly Cited
2004
Calcium (Ca2+)-induced Ca2+ release (CICR) in cardiac myocytes exhibits high gain and is graded. These properties result from… (More)
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Highly Cited
2003
Highly Cited
2003
Recent studies have demonstrated that transgenic (TG) expression of either Ca2+/calmodulin-dependent protein kinase IV (CaMKIV… (More)
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Review
2001
Review
2001
RyR and InsP3R are Ca(2+)-release channels. When induced to open by the appropriate stimulus, these channels allow Ca2+ to leave… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In the pathogenesis of cardiac dysfunction in heart failure, a decrease in the activity of the sarcoplasmic reticulum… (More)
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Highly Cited
1995
Highly Cited
1995
Ryanodine receptors (RyRs) are intracellular calcium release channels that participate in controlling cytosolic calcium levels… (More)
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