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RYR1 gene

Known as: PPP1R137, protein phosphatase 1, regulatory subunit 137, RYR1 
National Institutes of Health

Related topics

Related topics

2 relations
Ryanodine Receptor 1ryanodine receptor complex location

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart
Heart failure leads to dramatic electrophysiological remodelling as a result of numerous cellular and tissue‐level changes… 
Highly Cited
2012
Highly Cited
2012
Structural determination of the phosphorylation domain of the ryanodine receptor
The ryanodine receptor (RyR) is a large, homotetrameric sarcoplasmic reticulum membrane protein that is essential for Ca2… 
2009
2009
The effects of membrane potential, SR Ca2+ content and RyR responsiveness on systolic Ca2+ alternans in rat ventricular myocytes
Previous work has shown that small depolarizing pulses produce a beat to beat alternation in the amplitude of the systolic Ca2… 
Highly Cited
2005
Highly Cited
2005
Disruption of endoplasmic reticulum calcium stores is involved in neuronal death induced by glycolysis inhibition in cultured hippocampal neurons
Disturbances in neuronal calcium homeostasis have been implicated in a variety of neuropathological conditions, including… 
Highly Cited
2003
Highly Cited
2003
Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors.
The mechanisms by which non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) and rapamycin interact with ryanodine receptor (RyR… 
2003
2003
In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6.
The ryanodine receptor complex (RyR), a large oligomeric assembly that functions as a Ca(2+)-release channel in the sarcoplasmic… 
Highly Cited
2002
Highly Cited
2002
Distinct Intracellular Calcium Transients in Neurites and Somata Integrate Neuronal Signals
Intracellular calcium signals have distinct temporal and spatial patterns in neurons in which signal initiation and repetitive… 
2001
2001
Pharmacological characterization of the putative cADP-ribose receptor.
cADP-ribose (cADPR), a naturally occurring metabolite of NAD(+), has been shown to be an important regulator of intracellular Ca… 
Highly Cited
2000
Highly Cited
2000
Calcineurin regulates ryanodine receptor/Ca(2+)-release channels in rat heart.
The present study was undertaken to examine the physical and physiological interaction of protein phosphatase 2B, calcineurin… 
Highly Cited
1998
Highly Cited
1998
Cyclic stretch down-regulates calcium transporter gene expression in neonatal rat ventricular myocytes.
Abnormal intracellular Ca2+ handling in hypertrophied and failing hearts is partly due to changes in Ca2+ transporter gene… 
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