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RXFP2 gene

Known as: relaxin/insulin like family peptide receptor 2, LGR8, RXFP2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Functional implications of the utero-placental relaxin (RLN) system in the dog throughout pregnancy and at term.
Relaxin (RLN) is a key hormone of pregnancy in mammals best known for its involvement in connective tissue remodeling. In the… 
2015
2015
Expression of insulin-like factor 3 hormone-receptor system in the reproductive organs of male goats
Relaxin-like factor (RLF), generally known as insulin-like factor 3 (INSL3), is essential for testis descent during fetal… 
2014
2014
Dynamics of insulin-like factor 3 and its receptor expression in boar testes.
Relaxin-like factor (RLF), now mainly known as insulin-like factor 3 (INSL3), is essential for testis descent during fetal… 
2010
2010
An insight into testis and gubernaculum dynamics of INSL3-RXFP2 signalling during testicular descent in the dog.
Insulin-like 3 (INSL3) plays a prominent role in male development and is supposed to induce the growth of the gubernaculum testis… 
Review
2007
Review
2007
Relaxin-like ligand-receptor systems are autocrine/paracrine effectors in tumor cells and modulate cancer progression and tissue invasiveness.
Relaxin and INSL3 are novel autocrine/paracrine insulin-like hormones in tumor biology. Both effectors can bind to and activate… 
Highly Cited
2006
Highly Cited
2006
Expression of LGR7 and LGR8 by neonatal porcine uterine tissues and transmission of milk-borne relaxin into the neonatal circulation by suckling.
Estrogen receptor-dependent organizational events between birth [postnatal day (PND) 0] and PND 14 affect development and… 
2005
2005
Studies on Soluble Ectodomain Proteins of Relaxin (LGR7) and Insulin 3 (LGR8) Receptors
Abstract: The ectodomains of both the relaxin (LGR7) and the INSL3 (LGR8) receptors can be expressed on the cell surface using… 
2005
2005
Evolution of the Signaling System in Relaxin‐Family Peptides
Abstract: Recent studies have characterized two G‐protein‐coupled receptors (GPCRs), LGR7 and LGR8, as relaxin receptors. Later… 
2005
2005
Signaling Pathways of the LGR7 and LGR8 Receptors Determined by Reporter Genes
Abstract: Although much is known about the pleiotropic effects mediated by relaxin, the exact signaling pathways involved remain… 
2004
2004
Gene expression pattern and immunoreactive protein localization of LGR7 receptor in human endometrium throughout the menstrual cycle.
Relaxin (RLX) is a pregnancy-associated polypeptide hormone. In non-pregnant women, the peak of circulating relaxin coincides… 
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