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RUNX2 wt Allele

Known as: PEBP2A2, PEBP2aA1, CCD 
Human RUNX2 wild-type allele is located in the vicinity of 6p21 and is approximately 223 kb in length. This allele, which encodes runt-related… Expand
National Institutes of Health

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Bone matrix proteins are expressed in calcified arteries from dialysis patients, suggesting that vascular smooth… Expand
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Highly Cited
2003
Highly Cited
2003
Embryonic stem cells are pluripotent cells derived from the inner cell mass of mouse blastocysts that have been shown to… Expand
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Highly Cited
2002
Highly Cited
2002
Preclinical and clinical studies suggest a possible role for cyclooxygenases in bone repair and create concerns about the use of… Expand
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Highly Cited
2001
Highly Cited
2001
Transforming growth factor‐β (TGF‐β), a secreted factor present at high levels in bone, inhibits osteoblast differentiation in… Expand
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Highly Cited
2001
Highly Cited
2001
Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis during development, but little is known about… Expand
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Highly Cited
2000
Highly Cited
2000
Cbfa1 is a transcription factor that belongs to the runt domain gene family. Cbfa1-deficient mice showed a complete lack of bone… Expand
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Highly Cited
2000
Highly Cited
2000
The bone-specific transcription factor, Cbfa1, regulates expression of the osteocalcin (OCN) gene and is essential for bone… Expand
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Highly Cited
1999
Highly Cited
1999
Cbfa1, a transcription factor that belongs to the runt‐domain gene family, plays an essential role in osteogenesis. Cbfa1… Expand
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Review
1999
Review
1999
  • S. Mundlos
  • Journal of medical genetics
  • 1999
  • Corpus ID: 30069172
Cleidocranial dysplasia (CCD) (MIM 119600) is an autosomal dominant skeletal dysplasia characterised by abnormal clavicles… Expand
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Highly Cited
1997
Highly Cited
1997
A transcription factor, Cbfa1, which belongs to the runt-domain gene family, is expressed restrictively in fetal development. To… Expand
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