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RUNX2 wt Allele

Known as: PEBP2A2, PEBP2aA1, CCD 
Human RUNX2 wild-type allele is located in the vicinity of 6p21 and is approximately 223 kb in length. This allele, which encodes runt-related… 
National Institutes of Health

Related topics

Related topics

8 relations
6p21Cleidocranial DysplasiaHomo sapiensTranscription, Genetic

Broader (1)

RUNX2 gene

Papers overview

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Highly Cited
2013
Highly Cited
2013
Extracellular matrix protein adsorption to phosphate-functionalized gels from serum promotes osteogenic differentiation of human mesenchymal stem cells.
2012
2012
Lentiviral-Mediated RNAi Knockdown of Cbfa1 Gene Inhibits Endochondral Ossification of Antler Stem Cells in Micromass Culture
Articular cartilage (AC) lacks ability to repair defects due to its avascular nature as healing process relies on cells being… 
2006
2006
Gene regulation ex vivo within a wrap-around tendon.
This study tested the hypothesis that physiologic tendon loading modulates the fibrous connective tissue phenotype in… 
2005
2005
Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development.
AML1/Runx1 is a frequent target of human leukemia-associated gene aberration and encodes a transcription factor with nonredundant… 
2002
2002
Estrogen‐induced osteogenesis in mice is associated with the appearance of Cbfa1‐expressing bone marrow cells
Cbfa1 is a transcription factor recognised as being involved in early osteoblast differentiation during embryonic skeletogenesis… 
2002
2002
New mutations in the CBFA1 gene in two Mexican patients with cleidocranial dysplasia
Cleidocranial dysplasia (CCD) is an autosomal dominant skeletal disorder exhibiting a wide clinical spectrum ranging from minimal… 
2000
2000
Regulation of collagenase‐3 gene expression in osteoblastic and non‐osteoblastic cell lines
Collagenase‐3 expression in osteoblastic (UMR 106‐01, ROS 17/2.8) and non‐osteoblastic cell lines (BC1, NIH3T3) was examined. We… 
1997
1997
Induction of apoptosis in multidrug-resistant and radiation-resistant acute myeloid leukemia cells by a recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating…
Multiagent chemotherapy regimens fail to cure more than one-half of the patients with acute myeloid leukemia (AML) because of the… 
Review
1994
Review
1994
In vitro all-trans retinoic acid (ATRA) sensitivity and cellular retinoic acid binding protein (CRABP) levels in relapse leukemic cells after remission induction by ATRA in acute promyelocytic…
The current treatment of acute promyelocytic leukemia (APL, also called AML3 subtype) is focused on differentiating agents such… 
Highly Cited
1992
Highly Cited
1992
A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia.
The t(15;17) translocation is specifically observed in patients with promyelocytic leukemia (AML3). The chromosomal rearrangement… 
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