RUNX2 gene

Known as: AML3 GENE, PEBP2aA1, RUNX2 
This gene plays a role in both transcription and cell differentiation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2017
010020019712017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Prostate cancers show a slow progression from a local lesion (primary tumor) to a metastatic and hormone-resistant phenotype… (More)
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Highly Cited
2011
Highly Cited
2011
Reports of the bone-protective effects of resveratrol, a naturally occurring phytoestrogen and agonist for the longevity gene… (More)
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Highly Cited
2006
Highly Cited
2006
Mesenchymal stem cell-derived osteochondroprogenitors express two master transcription factors, SOX9 and RUNX2, during… (More)
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Highly Cited
2006
Highly Cited
2006
UNLABELLED RUNX2 expression in mesenchymal cells induces osteoblast differentiation and bone formation. BMP blocking agents were… (More)
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Highly Cited
2005
Highly Cited
2005
Both activating and null mutations of proteins required for canonical WNT signaling have revealed the importance of this pathway… (More)
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Highly Cited
2005
Highly Cited
2005
We recently identified a new acute myeloid leukemia (AML) subtype characterized by mutations at exon-12 of the nucleophosmin (NPM… (More)
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Highly Cited
2002
Highly Cited
2002
Core-binding factor β (CBFβ, also called polyomavirus enhancer binding protein 2β (PEBP2B)) is associated with an inversion of… (More)
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Highly Cited
2002
Highly Cited
2002
Runx2 (runt-related transcription factor 2, also known as Cbfa1, Osf2 and AML3) is essential for bone development in mice, and… (More)
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Highly Cited
2000
Highly Cited
2000
Cleidocranial dysplasia (CCD), an autosomal-dominant human bone disease, is thought to be caused by heterozygous mutations in… (More)
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Highly Cited
1994
Highly Cited
1994
cDNAs corresponding to three human runt domain containing genes, AML1, AML2, and AML3, were isolated and characterized. In… (More)
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