RUNX1T1 gene

Known as: ETO, RUNX1T1, RUNX1, TRANSLOCATED TO, 1 
This gene plays a role in transcriptional regulation and hematopoiesis.
National Institutes of Health

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Topic mentions per year

1944-2017
0102019442016

Papers overview

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Highly Cited
2001
Highly Cited
2001
t(8;21) and t(16;21) create two fusion proteins, AML-1-ETO and AML-1-MTG16, respectively, which fuse the AML-1 DNA binding domain… (More)
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Highly Cited
2000
Highly Cited
2000
RAR and AML1 transcription factors are found in leukemias as fusion proteins with PML and ETO, respectively. Association of PML… (More)
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Highly Cited
1998
Highly Cited
1998
The t(8;21) translocation between two genes known as AML1 and ETO is seen in approximately 12-15% of all acute myeloid leukemia… (More)
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Highly Cited
1998
Highly Cited
1998
t(8;21) is one of the most frequent translocations associated with acute myeloid leukemia. It produces a chimeric protein, acute… (More)
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Highly Cited
1998
Highly Cited
1998
Nuclear receptor corepressor (CoR)-histone deacetylase (HDAC) complex recruitment is indispensable for the biological activities… (More)
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Highly Cited
1998
Highly Cited
1998
The AML1 transcription factor and the transcriptional coactivators p300 and CBP are the targets of chromosome translocations… (More)
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Highly Cited
1993
Highly Cited
1993
The t(8;21) translocation is one of the most frequent chromosome abnormalities in acute myeloid leukemia. It has been shown that… (More)
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Highly Cited
1993
Highly Cited
1993
The success of posterior lumbar interbody fusion (PLIF) has been limited by mechanical and biologic deficiencies of the donor… (More)
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Highly Cited
1993
Highly Cited
1993
The translocation between chromosomes 8 and 21, t(8;21) (q22;q22), is the most frequent abnormality in acute myeloid leukemia… (More)
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Highly Cited
1992
Highly Cited
1992
We have developed a restriction map of the chromosome 21 breakpoint region involved in t(8;21)(q22;q22.3) acute myelogenous… (More)
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