Skip to search formSkip to main contentSkip to account menu

RUNX1T1 gene

Known as: ETO, RUNX1T1, RUNX1, TRANSLOCATED TO, 1 
This gene plays a role in transcriptional regulation and hematopoiesis.
National Institutes of Health

Related topics

Related topics

7 relations
AML1-ETO Fusion Protein ExpressionCBFA2T1 protein, humanHomo sapiensTranscriptional Regulation

Broader (1)

Genes

Narrower (1)

RUNX1T1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy.
The 8;21 chromosomal translocation occurs in 15% to 40% of patients with the FAB M2 subtype of acute myeloid leukemia (AML). This… 
2007
2007
Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.
2004
2004
Insertions generating the 5′RUNX1/3′CBFA2T1 gene in acute myeloid leukemia cases show variable breakpoints
Translocation t(8;21)(q22;q22) is a common karyotypic abnormality detected in about 15% of acute myeloid leukemia (AML) cases… 
2002
2002
XETOR regulates the size of the proneural domain during primary neurogenesis in Xenopus laevis
Highly Cited
2001
Highly Cited
2001
MTG8 proto-oncoprotein interacts with the regulatory subunit of type II cyclic AMP-dependent protein kinase in lymphocytes
AML1-MTG8 chimeric oncogene is generated in acute myelogenous leukemia with t(8;21), and seems to be responsible for the… 
2001
2001
Remission of Acute Myeloblastic Leukemia After Severe Pneumonia Treated With High-Dose Methylprednisolone
We report a case of acute myeloblastic leukemia (AML)-M2 (by French-American-British classification) with t(8;21) (q22;q22) that… 
2000
2000
A quantitative reverse transcriptase polymerase chain reaction method for the detection of leukaemic cells with t(8;21) in peripheral blood
Abstract: We evaluated the usefulness of a recently developed real‐time reverse transcriptase polymerase chain reaction (RT‐PCR… 
1998
1998
Subcellular localization of the oncoprotein MTG8 (CDR/ETO) in neural cells
The t(8;21) translocation associated with acute myeloid leukemia (AML) disrupts two genes, the AML1 gene also known as the core… 
1995
1995
Identification of two transcripts of AMLI/ETO‐fused gene in t(8;21) leukemic cells and expression of wild‐type ETO gene in hematopoietic cells
The t(8; 21) is a common chromosomal abnormality, preferentially associated with acute leukemia showing features of myeloid… 
1994
1994
Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2.
In the t(8;21) of acute myeloid leukemia (AML) M2, breakpoints are clustered on both chromosomes. The chromosome 21 breakpoint… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)