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RUNX1T1 wt Allele

Known as: ETO, CBFA2T1 Gene, RUNX1T1 
Human RUNX1T1 wild-type allele is located in the vicinity of 8q22 and is approximately 136 kb in length. This allele, which encodes protein CBFA2T1… 
National Institutes of Health

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Related topics

6 relations
8q22CBFA2T1 protein, humanHomo sapiensTranscriptional Regulation

Broader (1)

RUNX1T1 gene

Papers overview

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2015
2015
Runx1t1 Regulates the Neuronal Differentiation of Radial Glial Cells From the Rat Hippocampus
The brain has the highest Runx1t1 level relative to the levels in other organs. Runx1t1 might have a regulatory function as a… 
2014
2014
Runx1t1 (Runt-Related Transcription Factor 1; Translocated to, 1) Epigenetically Regulates the Proliferation and Nitric Oxide Production of Microglia
Background Microglia, the resident immune cells of the brain, undergo rapid proliferation and produce several proinflammatory… 
2002
2002
The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies
The MTG (Myeloid Translocation Gene) proteins are a family of novel transcriptional corepressors. We report that MTG16a, a… 
Highly Cited
2001
Highly Cited
2001
MTG8 proto-oncoprotein interacts with the regulatory subunit of type II cyclic AMP-dependent protein kinase in lymphocytes
AML1-MTG8 chimeric oncogene is generated in acute myelogenous leukemia with t(8;21), and seems to be responsible for the… 
2000
2000
In-Space Deployment Options for Large Space Solar Power Satellites
This research was performed at the Space Systems Design Lab at the Georgia Institute of Technology, Atlanta, GA, with the charter… 
1999
1999
Association of MTG8 (ETO/CDR), a Leukemia‐related Protein, with Serine/Threonine Protein Kinases and Heat Shock Protein HSP90 in Human Hematopoietic Cell Lines
A proto‐oncogene, MTG8 (ETO/CDR), is disrupted in the t(8;21) translocation associated with acute myeloid leukemia, and the gene… 
1998
1998
Polymorphism in the 3' untranslated region of MTG8 is associated with obesity in Pima Indian males.
Obesity has a genetic component and predisposes for the development of type 2 diabetes mellitus. One approach to identifying new… 
1998
1998
Subcellular localization of the oncoprotein MTG8 (CDR/ETO) in neural cells
The t(8;21) translocation associated with acute myeloid leukemia (AML) disrupts two genes, the AML1 gene also known as the core… 
1998
1998
Tumourigenicity of MTG8, a leukaemia‐related gene, in concert with v‐Ha‐ras gene in BALB/3T3 cells
The MTG8 (ETO) gene has been identified as the translocation partner of AML1 (PEBP2αB or CBFα2) gene in the AML1/MTG8 (ETO) fused… 
1997
1997
Significance of MTG8 in leukemogenesis.
MTG8 is a counterpart gene of AML1 in acute myeloid leukemia with t(8:21) translocation. Most of the coding region of the MTG8 is… 
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