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CBFA2T1 protein, human

Known as: ETO, ETO Protein, Protein ETO 
Protein CBFA2T1 (604 aa, ~68 kDa) is encoded by the human RUNX1T1 gene. This protein plays a role in the regulation of gene transcription.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Studies have documented the potential antitumor activities of oridonin, a compound extracted from medicinal herbs. However… Expand
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Review
2006
Review
2006
Recurring chromosome abnormalities are strongly associated with certain subtypes of leukemia, lymphoma and sarcomas. More… Expand
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Highly Cited
2006
Highly Cited
2006
AML1/ETO is the chimeric protein resulting from the t(8;21) in acute myeloid leukemia. The Nervy homology 2 (NHR2) domain in ETO… Expand
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Highly Cited
2004
Highly Cited
2004
The AML1-ETO fusion protein, generated by the t(8;21) chromosomal translocation, is causally involved in nearly 15% of acute… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract Subduction zones appear primarily controlled by the polarity of their direction, i.e., W-directed or E- to NNE-directed… Expand
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Highly Cited
1998
Highly Cited
1998
Chromosomal translocations in acute leukemia that affect the AML-1/CBFbeta transcription factor complex create dominant… Expand
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Highly Cited
1998
Highly Cited
1998
The t(8;21) translocation between two genes known as AML1 and ETO is seen in approximately 12-15% of all acute myeloid leukemia… Expand
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Highly Cited
1998
Highly Cited
1998
AML-1B is a hematopoietic transcription factor that is functionally inactivated by multiple chromosomal translocations in human… Expand
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Highly Cited
1997
Highly Cited
1997
Acute myeloid leukaemia (AMI) is a major haematopoietic malignancy characterized by the proliferation of a malignant clone of… Expand
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Review
1988
Review
1988
I Abbreviations used: ACTH, adrenocorticotropic hormone; ADCC, antibody-dependent cellular cytotoxicity; Bma .. total number of… Expand
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