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RU 58841
Known as:
RU-58841
, RU58841
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Imidazoles
Nitriles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Alternative synthesis of the anti-baldness compound RU58841
Matthew Leonard
,
A. Lingham
,
J. Niere
,
N. Jackson
,
P. G. Mckay
,
H. Hügel
2014
Corpus ID: 55586351
RU58841 is active against baldness and is commercially available. The previously reported synthesis uses phosgene, three discrete…
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Highly Cited
1998
Highly Cited
1998
Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells.
H. Miyamoto
,
S. Yeh
,
G. Wilding
,
C. Chang
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 42140830
Although hormone therapy with antiandrogens has been widely used for the treatment of prostate cancer, some antiandrogens may act…
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1998
1998
Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques
H. Pan
,
G. Wilding
,
+4 authors
Chawnshang Chang
Endocrine
1998
Corpus ID: 38619943
The effect of androgen receptor transcriptional activation by RU58841, a nonsteroidal anti-androgen, was studied in the human…
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1997
1997
Effects of topical antiandrogen and 5-alpha-reductase inhibitors on sebaceous glands in male fuzzy rats.
F. Ye
,
K. Imamura
,
N. Imanishi
,
L. Rhodes
,
H. Uno
Skin Pharmacology
1997
Corpus ID: 25277232
The fuzzy rat, a genetic mutant between hairless and hairy albino rats, expresses androgen-dependent hypersecretion of sebum and…
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1997
1997
A controlled study of the effects of RU58841, a non‐steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone‐conditioned nude mice
B. Brouwer
,
C. Tételin
,
T. Leroy
,
A. Bonfils
,
D. Neste
British Journal of Dermatology
1997
Corpus ID: 42827570
Summary Human hair growth can be monitored for several months after the transplantation of scalp samples from men with androgen…
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1997
1997
Dose-dependent and long term effects of RU58841 (androgen receptor blocker) on hair growth in the bald stumptailed Macaque.
E. Bayne
,
J. Flanagan
,
+7 authors
G. Harris
1997
Corpus ID: 88796963
Highly Cited
1997
Highly Cited
1997
Importance of sebaceous glands in cutaneous penetration of an antiandrogen: target effect of liposomes.
E. Bernard
,
J. Dubois
,
J. Wepierre
Journal of Pharmacy and Science
1997
Corpus ID: 46197519
The significance of the sebaceous gland pathway in the cutaneous permeation of an antiandrogen, 4-[3-(4-hydroxybutyl)-4,4…
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1995
1995
Local Inhibition of Sebaceous Gland Growth by Topically Applied RU 58841
J. Matias
,
M. Gaillard
Annals of the New York Academy of Sciences
1995
Corpus ID: 45086788
The biological activity of a series of nonsteroidal, pure androgen receptor inhibitors was compared using the Syrian hamster ear…
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1995
1995
Follicular regrowth with 5 α-reductase inhibitor (finasteride) or androgen receptor blocker (RU58841) in the bald scalp of the stumptailed macaque.
H. Uno
,
N. Obana
,
A. Cappas
,
L. Rhodes
,
A. Bonfils
1995
Corpus ID: 91030189
1994
1994
Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
D. Cousty-Berlin
,
B. Bergaud
,
M. Bruyant
,
T. Battmann
,
C. Branche
,
D. Philibert
Journal of Steroid Biochemistry and Molecular…
1994
Corpus ID: 29752252
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