RU 58841

Known as: RU-58841, RU58841 
 
National Institutes of Health

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2014
2014
Alternative synthesis of the anti-baldness compound RU58841
RU58841 is active against baldness and is commercially available. The previously reported synthesis uses phosgene, three discrete… (More)
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2001
2001
Synthesis and structure-activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands.
A series of arylhydantoin derivatives modeled after the antiandrogen RU 58841 was generated to identify potential candidates for… (More)
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1998
1998
Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques
The effect of androgen receptor transcriptional activation by RU58841, a nonsteroidal anti-androgen, was studied in the human… (More)
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1998
1998
The effect of topical RU58841 (androgen receptor blocker) combined with minoxidil on hair growth in macaque androgenetic alopecia
 
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1997
1997
Effects of topical antiandrogen and 5-alpha-reductase inhibitors on sebaceous glands in male fuzzy rats.
The fuzzy rat, a genetic mutant between hairless and hairy albino rats, expresses androgen-dependent hypersecretion of sebum and… (More)
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1997
1997
A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice.
Human hair growth can be monitored for several months after the transplantation of scalp samples from men with androgen-dependent… (More)
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1997
1997
Dose-dependent and long term effects of RU58841 (androgen receptor blocker) on hair growth in the bald stumptailed Macaque.
 
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1997
1997
Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpubertal stumptailed macaque.
Hair-follicle regression in the bald scalps of stumptailed macaques develops after puberty, which corresponds to an elevation of… (More)
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1995
1995
Local inhibition of sebaceous gland growth by topically applied RU 58841.
The biological activity of a series of nonsteroidal, pure androgen receptor inhibitors was compared using the Syrian hamster ear… (More)
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1994
1994
RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism
A new topically active non-steroidal antiandrogen, RU 58841 has been synthesized. It displays high affinity for the hamster… (More)
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