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RTI 121

Known as: 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(4-iodophenyl)-8-methyl-, 1-methylethyl ester, (1R-(exo,exo))-, RTI-121 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cocaine
analogs & derivatives

Papers overview

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2013
2013
Effect of Maternal Lipopolysaccharide Administration on the Development of Dopaminergic Receptors and Transporter in the Rat Offspring
Epidemiological evidence supports that maternal infection during gestation are notable risk factors for developmental mental… Expand
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2005
2005
Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and…
Analogs of benztropine (BZT) bind to the dopamine (DA) transporter and inhibit DA uptake but often have behavioral effects that… Expand
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2003
2003
Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Nigrostriatal damage leads to a reduction in striatal nicotinic acetylcholine receptors (nAChRs) in rodents, monkeys, and… Expand
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Highly Cited
2001
Highly Cited
2001
Chronic L-DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6-OHDA or FeCl(3) nigrostriatal…
In this study, we have examined the effects of chronic L-3,4-dihydroxyphenylalanine (L-DOPA) administration on the remaining… Expand
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2000
2000
Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects
Abstract  Rationale: The discriminative-stimulus effects of cocaine have been reported to be mediated by indirect agonist actions… Expand
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1997
1997
Potential misconceptions in dopamine transporter assays arising from the binding of [125I]RTI-121 to filters: effect of ions and cocaine
Binding of the cocaine analog 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121) to… Expand
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1996
1996
Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.
The cocaine analogue RTI-121 (3 beta-(4-iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester), when labeled with carbon-11… Expand
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1996
1996
Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
Three cocaine analogs were compared with cocaine for the capacity to affect: (1) dopamine transporter binding and function; and… Expand
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1996
1996
Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3 beta-(4-[125I]iodophenyl) tropan-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121).
A selective ligand for the dopamine transporter 3 beta-(4-iodophenyl)tropan-2 beta-carboxylic acid isopropyl ester (RTI-121) has… Expand
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1995
1995
Mapping dopamine transporters in the human brain with novel selective cocaine analog [125I]RTI-121.
The novel cocaine analog RTI-121 [3 beta-(4-iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester] was evaluated as a probe… Expand
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