FAQ

RTI 121

Known as: 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(4-iodophenyl)-8-methyl-, 1-methylethyl ester, (1R-(exo,exo))-, RTI-121 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
012319952017

Related topics

Related topics

2 relations

Broader (1)

Cocaine
analogs & derivatives

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
RTI 121
Cocaine
analogs & derivatives

Papers overview

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2003
2003
Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Nigrostriatal damage leads to a reduction in striatal nicotinic acetylcholine receptors (nAChRs) in rodents, monkeys, and… (More)
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2001
2001
Chronic L-DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6-OHDA or FeCl(3) nigrostriatal…
In this study, we have examined the effects of chronic L-3,4-dihydroxyphenylalanine (L-DOPA) administration on the remaining… (More)
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2000
2000
Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects
Rationale: The discriminative-stimulus effects of cocaine have been reported to be mediated by indirect agonist actions initiated… (More)
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1998
1998
Multiple binding sites for [125I]RTI-121 and other cocaine analogs in rat frontal cerebral cortex.
In an effort to identify novel binding sites for cocaine and its analogs, we carried out binding studies with the high-affinity… (More)
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1997
1997
Potential misconceptions in dopamine transporter assays arising from the binding of [125I]RTI-121 to filters: effect of ions and cocaine.
Binding of the cocaine analog 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121) to… (More)
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1996
1996
Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3 beta-(4-[125I]iodophenyl) tropan-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121).
A selective ligand for the dopamine transporter 3 beta-(4-iodophenyl)tropan-2 beta-carboxylic acid isopropyl ester (RTI-121) has… (More)
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1996
1996
Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.
The cocaine analogue RTI-121 (3 beta-(4-iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester), when labeled with carbon-11… (More)
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1996
1996
Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
Three cocaine analogs were compared with cocaine for the capacity to affect: (1) dopamine transporter binding and function; and… (More)
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1995
1995
Mapping dopamine transporters in the human brain with novel selective cocaine analog [125I]RTI-121.
The novel cocaine analog RTI-121 [3 beta-(4-iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester] was evaluated as a probe… (More)
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1995
1995
Rate of binding of various inhibitors at the dopamine transporter in vivo
The rate of entry of drugs into brain is thought to be a factor in their abuse liability. In this investigation, we have examined… (More)
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