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RTI 121
Known as:
8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(4-iodophenyl)-8-methyl-, 1-methylethyl ester, (1R-(exo,exo))-
, RTI-121
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Cocaine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Combined in vitro and in silico approaches to the assessment of stimulant properties of novel psychoactive substances – The case of the benzofuran 5-MAPB
M. Sahai
,
C. Davidson
,
+4 authors
J. Opacka‐Juffry
Progress in Neuro-psychopharmacology and…
2017
Corpus ID: 30943496
2013
2013
Effect of Maternal Lipopolysaccharide Administration on the Development of Dopaminergic Receptors and Transporter in the Rat Offspring
M. Baharnoori
,
S. Bhardwaj
,
L. Srivastava
PLoS ONE
2013
Corpus ID: 6748053
Epidemiological evidence supports that maternal infection during gestation are notable risk factors for developmental mental…
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2005
2005
Relationship between in Vivo Occupancy at the Dopamine Transporter and Behavioral Effects of Cocaine, GBR 12909 [1-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and…
R. Desai
,
T. Kopajtic
,
D. French
,
A. Newman
,
J. Katz
Journal of Pharmacology and Experimental…
2005
Corpus ID: 19298656
Analogs of benztropine (BZT) bind to the dopamine (DA) transporter and inhibit DA uptake but often have behavioral effects that…
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Highly Cited
2003
Highly Cited
2003
Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
M. Quik
,
J. Sum
,
+6 authors
S. Grady
Molecular Pharmacology
2003
Corpus ID: 13219471
Nigrostriatal damage leads to a reduction in striatal nicotinic acetylcholine receptors (nAChRs) in rodents, monkeys, and…
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Highly Cited
2001
Highly Cited
2001
Chronic L‐DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6‐OHDA or FeCl3 nigrostriatal…
K. Datla
,
S. Blunt
,
D. Dexter
Movement Disorders
2001
Corpus ID: 8097512
In this study, we have examined the effects of chronic L‐3,4‐dihydroxyphenylalanine (L‐DOPA) administration on the remaining…
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2001
2001
Locomotor stimulant effects of novel phenyltropanes in the mouse.
H. Kimmel
,
F. Carroll
,
M. Kuhar
Drug and Alcohol Dependence
2001
Corpus ID: 46212104
Highly Cited
2000
Highly Cited
2000
Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects
J. Katz
,
S. Izenwasser
,
P. Terry
Psychopharmacology
2000
Corpus ID: 1907433
Abstract Rationale: The discriminative-stimulus effects of cocaine have been reported to be mediated by indirect agonist actions…
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1997
1997
Characterization of [125I]RTI-121 binding to dopamine transporter in vitro.
N. Chen
,
J. H. Ding
,
Y. Wang
Zhongguo yao li xue bao = Acta pharmacologica…
1997
Corpus ID: 20496443
AIM To characterize the binding of [125I]3 beta-(4-iodophenyl) tropane-2 beta-carboxylic acid isopropyl ester (RTI-121) to the…
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1996
1996
Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
A. Fleckenstein
,
T. Kopajtic
,
J. Boja
,
F. Carroll
,
M. Kuhar
European Journal of Pharmacology
1996
Corpus ID: 33813884
Highly Cited
1995
Highly Cited
1995
Mapping dopamine transporters in the human brain with novel selective cocaine analog [125I]RTI‐121
J. Staley
,
J. Boja
,
+5 authors
D. Mash
Synapse
1995
Corpus ID: 20623047
The novel cocaine analog RTI‐121[3β‐(4‐iodophenyl)tropane‐2β‐carboxylic acid isopropyl ester] was evaluated as a probe for the in…
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