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RTI 121

Known as: 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(4-iodophenyl)-8-methyl-, 1-methylethyl ester, (1R-(exo,exo))-, RTI-121 
National Institutes of Health

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2 relations

Broader (1)

Cocaine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Combined in vitro and in silico approaches to the assessment of stimulant properties of novel psychoactive substances – The case of the benzofuran 5-MAPB
2013
2013
Effect of Maternal Lipopolysaccharide Administration on the Development of Dopaminergic Receptors and Transporter in the Rat Offspring
Epidemiological evidence supports that maternal infection during gestation are notable risk factors for developmental mental… 
2005
2005
Relationship between in Vivo Occupancy at the Dopamine Transporter and Behavioral Effects of Cocaine, GBR 12909 [1-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and…
Analogs of benztropine (BZT) bind to the dopamine (DA) transporter and inhibit DA uptake but often have behavioral effects that… 
Highly Cited
2003
Highly Cited
2003
Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Nigrostriatal damage leads to a reduction in striatal nicotinic acetylcholine receptors (nAChRs) in rodents, monkeys, and… 
Highly Cited
2001
Highly Cited
2001
Chronic L‐DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6‐OHDA or FeCl3 nigrostriatal…
In this study, we have examined the effects of chronic L‐3,4‐dihydroxyphenylalanine (L‐DOPA) administration on the remaining… 
2001
2001
Locomotor stimulant effects of novel phenyltropanes in the mouse.
Highly Cited
2000
Highly Cited
2000
Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects
Abstract  Rationale: The discriminative-stimulus effects of cocaine have been reported to be mediated by indirect agonist actions… 
1997
1997
Characterization of [125I]RTI-121 binding to dopamine transporter in vitro.
AIM To characterize the binding of [125I]3 beta-(4-iodophenyl) tropane-2 beta-carboxylic acid isopropyl ester (RTI-121) to the… 
1996
1996
Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
Highly Cited
1995
Highly Cited
1995
Mapping dopamine transporters in the human brain with novel selective cocaine analog [125I]RTI‐121
The novel cocaine analog RTI‐121[3β‐(4‐iodophenyl)tropane‐2β‐carboxylic acid isopropyl ester] was evaluated as a probe for the in… 
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