RSPO2 gene

Known as: CRISTIN2, R-spondin 2, R-Spondin 2 Gene 
This gene plays a role in both Wnt signaling and embryonic morphogenesis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
0102020072017

Papers overview

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2016
2016
R-spondin proteins are identified as secreted agonists of the canonical Wnt/β-catenin signaling pathway, and leucine-rich repeat… (More)
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2015
2015
Cancer stem cells (CSC) present a formidable clinical challenge by escaping therapeutic intervention and seeding tumors through… (More)
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2014
2014
R-spondins are a family of secreted Wnt agonists. One of the family members, R-spondin 2 (RSPO2), has an important role in… (More)
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Highly Cited
2014
Highly Cited
2014
UNLABELLED Hepatic resection is the most curative treatment option for early-stage hepatocellular carcinoma, but is associated… (More)
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2012
Highly Cited
2012
Identifying and understanding changes in cancer genomes is essential for the development of targeted therapeutics. Here we… (More)
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2010
2010
We recently showed that genes at 3 loci account for the majority of variation in canine fur. Allelic variation at genes… (More)
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2010
2010
Advances in genomics and proteomics permit rapid identification of disease-relevant genes and proteins. Challenges include… (More)
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Highly Cited
2009
Highly Cited
2009
Human colorectal cancers (CRCs) display a large number of genetic and epigenetic alterations, some of which are causally involved… (More)
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Highly Cited
2009
Highly Cited
2009
Coat color and type are essential characteristics of domestic dog breeds. Although the genetic basis of coat color has been well… (More)
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Highly Cited
2008
Highly Cited
2008
Herein, we demonstrate that Lrp6-mediated R-spondin 2 signaling through the canonical Wnt pathway is required for normal… (More)
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