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RSPO2 gene

Known as: CRISTIN2, R-spondin 2, R-Spondin 2 Gene 
This gene plays a role in both Wnt signaling and embryonic morphogenesis.
National Institutes of Health

Papers overview

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2018
2018
The four R-spondin secreted ligands (RSPO1–RSPO4) act via their cognate LGR4, LGR5 and LGR6 receptors to amplify WNT signalling1… Expand
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2015
2015
Cancer stem cells (CSC) present a formidable clinical challenge by escaping therapeutic intervention and seeding tumors through… Expand
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2015
2015
The four secreted R-spondin (Rspo1-4) proteins of vertebrates function as stem cell growth factors and potentiate canonical Wnt… Expand
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2014
2014
R-spondins are a family of secreted Wnt agonists. One of the family members, R-spondin 2 (RSPO2), has an important role in… Expand
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Highly Cited
2014
Highly Cited
2014
UNLABELLED Hepatic resection is the most curative treatment option for early-stage hepatocellular carcinoma, but is associated… Expand
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2012
2012
Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flexion contractures. We… Expand
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Highly Cited
2009
Highly Cited
2009
Human colorectal cancers (CRCs) display a large number of genetic and epigenetic alterations, some of which are causally involved… Expand
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Highly Cited
2009
Highly Cited
2009
Dog Coats Shed Genetic Secrets The coats of domestic dogs show great variation—long, short, straight, wavy, curly, wiry, or… Expand
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Highly Cited
2008
Highly Cited
2008
The R-Spondin (RSpo) family of secreted proteins is implicated in the activation of the Wnt signaling pathway. Despite the high… Expand
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