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RSPO2 gene

Known as: CRISTIN2, R-spondin 2, R-Spondin 2 Gene 
This gene plays a role in both Wnt signaling and embryonic morphogenesis.
National Institutes of Health

Related topics

Related topics

5 relations
Limb DevelopmentMorphogenesisR-Spondin-2Signal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
RSPO2 enhances cell invasion and migration via the WNT/β‐catenin pathway in human gastric cancer
R‐spondins comprise a group of secreted WNT agonists. R‐spondin2 (RSPO2) plays a crucial role in the activation of the WNT… 
2018
2018
Genome wide association study on feed conversion ratio using imputed sequence data in chickens
Objective Feed consumption contributes a large percentage for total production costs in the poultry industry. Detecting genes… 
Review
2017
Review
2017
Novel Insights into Gastric Cancer: Methylation of R-spondins and Regulation of LGR5 by SP1
Recently, it was shown that leucine-rich repeat-containing receptor 5 (LGR5)–expressing stem cells are the cellular origin of… 
2016
2016
N-Glycosylation of Human R-Spondin 1 Is Required for Efficient Secretion and Stability but Not for Its Heparin Binding Ability
R-spondin 1 (Rspo1) plays an essential role in stem cell biology by potentiating Wnt signaling activity. Despite the fact that… 
2016
2016
R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice
The R-spondin family of proteins has recently been described as secreted enhancers of β-catenin activation through the canonical… 
2015
2015
Roles of miR-196a on gene regulation of neuroendocrine tumor cells
2015
2015
Engineering High-Potency R-spondin Adult Stem Cell Growth Factors
Secreted R-spondin proteins (RSPOs1–4) function as adult stem cell growth factors by potentiating Wnt signaling. Simultaneous… 
2015
2015
Pancreatic CSCs and microenvironment
Pancreatic ductal adenocarcinoma (PDAC) is the most common malignant neoplasm of the pancreas and presents with dismal prognosis… 
2013
2013
Virulence of infecting Helicobacter pyloristrains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae
DNA methylation changes are known to occur in gastric cancers and in premalignant lesions of the gastric mucosae. In order to… 
2012
2012
Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells
Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse… 
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