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R-Spondin-2

Known as: Roof Plate-Specific Spondin-2, hRspo2 
R-spondin-2 (243 aa, ~28 kDa) is encoded by the human RSPO2 gene. This protein plays a role in beta-catenin-mediated signaling and bone, limb and… 
National Institutes of Health

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Related topics

7 relations
Extracellular SpaceLimb DevelopmentMorphogenesisRSPO2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
C‑mannosylation of R‑spondin2 activates Wnt/β‑catenin signaling and migration activity in human tumor cells.
R‑spondin2 (Rspo2), one of the four members of the R‑spondin family of proteins, has agonistic activity in the Wnt/β‑catenin… 
2018
2018
R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass
The R-spondin family of proteins are Wnt agonists, and the complete embryonic disruption of Rspo2 results in skeletal… 
2017
2017
R-Spondin-2 Modulates Osteoblastogenesis and Bone Accrual
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2017
2017
Concentration of R-spondin 2 in the Follicular Fluid is Correlated with Oocyte Number and Metaphase II Oocytes in Iraqi Women Undergo ICSI
Background: R-spondin2is a protein expressed in the ovary at specific stages of follicular development the effect of Rspondin-2… 
2014
2014
R-Spondin2 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis
BackgroundThe development of liver fibrosis is the fundamental stage toward a number of mortal complications of liver diseases… 
Review
2010
Review
2010
Thrombospondins and Novel TSR-containing Proteins, R-spondins, Regulate Bone Formation and Remodeling
Thrombospondins (TSPs) are a family of five secreted multimeric matricellular proteins that share homology in the type II and III… 
Highly Cited
2009
Highly Cited
2009
Coat Variation in the Domestic Dog Is Governed by Variants in Three Genes
Dog Coats Shed Genetic Secrets The coats of domestic dogs show great variation—long, short, straight, wavy, curly, wiry, or… 
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