Limb Development

Interdependent positional signaling by the apical ectodermal ridge, the posterior mesenchyme zone of polarizing activity, and the non ridge ectoderm… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The potential role of Hox genes during vertebrate limb development was brought into focus by gene expression analyses in mice (P… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
To determine the role of fibroblast growth factor (FGF) signalling from the apical ectodermal ridge (AER), we inactivated Fgf4… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2001
Review
2001
Vertebrate limb buds are embryonic structures for which much molecular and cellular data are known regarding the mechanisms that… (More)
  • figure 1
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The interactions between fibroblast growth factors (FGF) and their receptors have important roles in mediating mesenchymal… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
We provide evidence that FGF8 serves as an endogenous inducer of chick limb formation and that its expression in the intermediate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The vertebrate Hox genes have been shown to be important for patterning the primary and secondary axes of the developing… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
1995
Review
1995
The recent identification of Wnt-7a as a signalling molecule in dorsal/ventral patterning means that we now have a known signal… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The Drosophila hedgehog (hh) gene encodes a secreted protein involved in organizing growth and patterning in many developmental… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1993
Highly Cited
1993
The apical ectodermal ridge plays a key role in limb development. We show that recombinant FGF-4 can substitute for the ridge to… (More)
Is this relevant?
Highly Cited
1977
Highly Cited
1977
Quail-to-chick grafting experiments performed during the third day of incubation demonstrate that somites can contribute to limb… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 5
Is this relevant?