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Limb Development

Interdependent positional signaling by the apical ectodermal ridge, the posterior mesenchyme zone of polarizing activity, and the non ridge ectoderm… 
National Institutes of Health

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ALX4 geneALX4 wt AlleleBiologic DevelopmentCD44 protein, human

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limb morphogenesisnail development

Papers overview

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2009
2009
Ectopic Meis 1 expression in the mouse limb bud alters PD patterning in a Pbx 1-independent manner
During limb development, expression of the TALE homeobox transcription factor Meis1 is activated by retinoic acid in the proximal… 
1998
1998
Limb development in the Pacific giant salamanders, Dicamptodon (Amphibia, Caudata, Dicamptodontidae)
The larvae of Pacific giant salamanders, Dicamptodon (Dicamptodontidae), develop in streams, display precocious limb development… 
1994
1994
The genetics of human limb development.
The events of early limb development are similar for all tetrapods in that they define patterning in both the proxi-mal/distal (P… 
Highly Cited
1990
Highly Cited
1990
An extracellular matrix molecule of newt and axolotl regenerating limb blastemas and embryonic limb buds: immunological relationship of MT1 antigen with tenascin.
Several well-characterized extracellular matrix (ECM) components have been localized to the amphibian limb regenerate, but the… 
1987
1987
Evidence for negative control of growth by adenosine in the mammalian embryo: induction of Hmx/+ mutant limb outgrowth by adenosine deaminase.
We investigated the growth-regulatory actions of adenosine and adenosine deaminase (ADA) during embryonic limb development in the… 
1986
1986
Differential effects of 4-hydroperoxycyclophosphamide on limb development in vitro.
Cyclophosphamide must be metabolically activated to produce malformations in limbs developing in culture; 4… 
1981
1981
Experiments on Anuran limb buds and their significance for principles of vertebrate limb development.
A standard set of six experiments performed on the limb buds of two species of Anurans - Rana temporaria and Xenopus laevis - are… 
1976
1976
Direct exposure of postimplantation mouse embryos to 5-bromodeoxyuridine in vitro and its effect on subsequent chondrogenesis in the limbs.
As maternally administered 5-bromodeoxyuridine (BudR) is very quickly degraded by the liver, a combination of whole embryo… 
1975
1975
Limb development in mouse embryos: protection against teratogenic effects of 6-diazo-5-ox-L-norleucine (DON) in vivo and in vitro.
The glutamine analogue, 6-diazo-5-oxo-L-norleucine (DON), has been shown to inhibit biosynthesis of purines and… 
Review
1972
Review
1972
Is abnormal limb bud morphology in the mutant talpid 2 chick embryo a result of altered intercellular adhesion? Studies employing cell sorting and fragment fusion.
Reprinted from THE JOURNAL or EXPERIMENTAL ZOOLOGY Vol. 181, No. 1, July 1972 © The Wistar Institute Press 1972 Is Abnormal Limb… 
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