limb morphogenesis

The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion… (More)
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Studies of the vertebrate limb development have contributed significantly to understanding the fundamental mechanisms underlying… (More)
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Highly Cited
2004
Highly Cited
2004
The mouse limb deformity (ld) mutations cause limb malformations by disrupting epithelial-mesenchymal signaling between the… (More)
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2004
2004
In humans and mice, loss of HOXA13 function causes defects in the growth and patterning of the digits and interdigital tissues… (More)
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Highly Cited
2001
Highly Cited
2001
Dickkopf1 (Dkk1) is a secreted protein that acts as a Wnt inhibitor and, together with BMP inhibitors, is able to induce the… (More)
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Highly Cited
1998
Highly Cited
1998
In the final stages of limb morphogenesis, autopodial cells leaving the progress zone differentiate into cartilage or undergo… (More)
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Review
1998
Review
1998
Morphogenesis is the developmental cascade of pattern formation and body plan establishment, culminating in the adult form. It… (More)
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Highly Cited
1997
Highly Cited
1997
Chondrodysplasia Grebe type (CGT) is an autosomal recessive disorder characterized by severe limb shortening and dysmorphogenesis… (More)
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Highly Cited
1997
Highly Cited
1997
Bone Morphogenetic Protein 2 (BMP-2) and Osteogenic Protein 1 (OP-1, also termed BMP-7) are members of the transforming growth… (More)
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Highly Cited
1996
Highly Cited
1996
Tetrapod fore-and hindlimbs have evolved from the pectoral and pelvic fins of an ancient vertebrate ancestor. In this ancestor… (More)
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Highly Cited
1975
Highly Cited
1975
The interpretation of positional information can provide the basis for pattern formation in limb morphogenesis. The gradient in… (More)
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