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The regulatory specificity of enhancers and their interaction with gene promoters is thought to be controlled by their sequence… Expand A table of developmental stages of the target species is useful for studying the development of any animal. Although tables of… Expand Dickkopf1 (Dkk1) is a secreted protein that acts as a Wnt inhibitor and, together with BMP inhibitors, is able to induce the… Expand Morphogenesis is the developmental cascade of pattern formation and body plan establishment, culminating in the adult form. It… Expand In the final stages of limb morphogenesis, autopodial cells leaving the progress zone differentiate into cartilage or undergo… Expand During early stages of chick limb development, the homeobox-containing gene Msx-2 is expressed in the mesoderm at the anterior… Expand Chondrodysplasia Grebe type (CGT) is an autosomal recessive disorder characterized by severe limb shortening and dysmorphogenesis… Expand Bone Morphogenetic Protein 2 (BMP-2) and Osteogenic Protein 1 (OP-1, also termed BMP-7) are members of the transforming growth… Expand Tetrapod fore-and hindlimbs have evolved from the pectoral and pelvic fins of an ancient vertebrate ancestor. In this ancestor… Expand The interpretation of positional information can provide the basis for pattern formation in limb morphogenesis. The gradient in… Expand