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RPMI-8226

A lymphoblast-like cell line established from the peripheral blood of a 61 year old male patient with multiple myeloma (IgG lambda-type).
National Institutes of Health

Papers overview

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2018
2018
Knockdown of REGγ inhibits the proliferation and migration and promotes the apoptosis of multiple myeloma cells by downregulating NF-κB signal pathway
ABSTRACT Objectives: This study aimed to evaluate the effects of REGγ knockdown on the proliferation, apoptosis and migration of… 
2017
2017
Construction of a recombinant lentivirus-mediated shRNA expression vector targeting the human PSMD10 gene and validation of RNAi efficiency in RPMI-8226 multiple myeloma cells
Multiple myeloma (MM) is one of the most common malignant blood cancers. Previous studies have reported that proteasome 26S… 
2014
2014
Inhibition of mTOR with everolimus and silencing by vascular endothelial cell growth factor-specific siRNA induces synergistic antitumor activity in multiple myeloma cells
Angiogenesis has an important role in the pathogenesis and progression of multiple myeloma (MM). MM cells secrete vascular… 
2012
2012
The sitotoxic effect of gemcitabine on multiple myeloma (RPMI-8226) and Ig G plasma cell leukemia (ARH 77) cell lines -
As a hematological malignancy, multiple myeloma is a plasma cell discrasia that begins insidiously and usually shows a slow… 
2011
2011
Cytotoxic effect of docetaxel on multiple myeloma cell lines (RPMI-8226) as a chemotherapotic agent -
Docetaxel that causes microtubule stabilization during mitotic spindle organizing in cell and forces the cell to go apopitosis… 
2011
2011
Triptolide-induced apoptosis by inactivating nuclear factor-kappa B apoptotic pathway in multiple myeloma in vitro
The effect of triptolide on proliferation and apoptosis of human multiple myeloma RPMI-8226 cells in vitro, as well as the roles… 
2010
2010
Effect of β-elemene on proliferation of human multiple myeloma cells RPMI-8226
Objective To investigate the effects of β-elemene on proliferation,cell cycle and apoptosis of human multiple myeloma RPMI-8226… 
1995
1995
Voltage-dependent inactivation of volume-regulated Cl− current in human T84 colonic and B-cell myeloma cell lines
The voltage-dependent inactivation of a volume-regulated Cl− current (VRChlC) in an epithelial (T84), and a B cell myeloma (RPMI… 
1986
1986
Interferons in the treatment of multiple myeloma.
Recombinant DNA technology has made adequate quantities of human interferons available for both in vitro and in vivo testing. In… 
1979
1979
Human myeloma cells and their strong stimulating capacity in 'one-way' mixed lymphocyte reaction: a comparative study with leukaemic B lymphoid cells.
Cultured human myeloma cells (ARH-77, RPMI-8226 and U-266), like leukaemic B lymphoid cells, consistently exerted a strong…