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RPMI-8226

A lymphoblast-like cell line established from the peripheral blood of a 61 year old male patient with multiple myeloma (IgG lambda-type).
National Institutes of Health

Papers overview

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2013
2013
Triazole-based inhibitors of geranylgeranyltransferase II.
2012
2012
Synthesis and antileukemic activity of 16E-[4-(2-carboxy)ethoxybenzylidene]-androstene amides
Highly Cited
2009
Highly Cited
2009
Regioselective synthesis and stereochemical structure of anti-tumor active dispiro[3H-indole-3,2'-pyrrolidine-3',3''-piperidine]-2(1H),4''-diones.
  • A. S. Girgis
  • European journal of medicinal chemistry
  • 2009
  • Corpus ID: 1860783
2009
2009
All‐trans retinoic acid can intensify the growth inhibition and differentiation induction effect of rosiglitazone on multiple myeloma cells
Objective:  Activation of PPARγ by its ligands has shown potential anti‐neoplastic effects in solid tumors. In this study, we… 
Highly Cited
2008
Highly Cited
2008
Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth
Bisphosphonates (BPs) are effective inhibitors of tumor-induced bone resorption. Recent studies have demonstrated that BPs… 
2007
2007
Synthesis of novel 3-amino-2-(4-chloro-2-mercaptobenzenesulfonyl)-guanidine derivatives as potential antitumor agents.
Highly Cited
2003
Highly Cited
2003
The Bisphosphonate Zoledronic Acid Induces Cytotoxicity in Human Myeloma Cell Lines with Enhancing Effects of Dexamethasone and Thalidomide
Bisphosphonates have recently been introduced in the therapeutic armamentarium for long-term treatment of patients with multiple… 
Highly Cited
2002
Highly Cited
2002
Growth inhibition and apoptosis of myeloma cells by the CDK inhibitor flavopiridol.
Highly Cited
2002
Highly Cited
2002
Identification of downstream genes up‐regulated by the tumor necrosis factor family member TALL‐1
TALL‐1 is a member of the tumor necrosis factor family that binds to BCMA, TACI, and BAFF‐R, three receptors mostly expressed by… 
1999
1999
Isolation of human lymphocyte antigens class I-restricted cytotoxic T lymphocytes against autologous myeloma cells.
Peripheral blood T cells from a patient with multiple myeloma in complete remission were selected in vitro against an autologous… 
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