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RPMI-8226

A lymphoblast-like cell line established from the peripheral blood of a 61 year old male patient with multiple myeloma (IgG lambda-type).
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
It has been determined that long noncoding RNAs (lncRNAs) are identified as a potential regulatory factor in multiple tumors as… Expand
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Highly Cited
2010
Highly Cited
2010
Cucurbitacin B is a natural anti-cancer compound found in Cucurbitaceae. Although the anti-cancer activity of cucurbitacin B in… Expand
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Highly Cited
2007
Highly Cited
2007
Targeting the ubiquitin-proteasome pathway has emerged as a potent anticancer strategy. Bortezomib, a specific proteasome… Expand
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Highly Cited
2005
Highly Cited
2005
Multiple myeloma (MM) is an incurable plasma cell (PC) malignancy able to mediate massive destruction of the axial and… Expand
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Highly Cited
2004
Highly Cited
2004
IL-6 has been reported to play a central role in growth and survival of multiple myeloma (MM) cells. However, recently we have… Expand
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Highly Cited
2003
Highly Cited
2003
Smac, second mitochondria-derived activator of caspases, promotes apoptosis via activation of caspases. Heat shock protein 27… Expand
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Highly Cited
2002
Highly Cited
2002
The proteasome is a ubiquitous and essential intracellular enzyme that degrades many proteins regulating cell cycle, apoptosis… Expand
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Highly Cited
1999
Highly Cited
1999
Activity guided fractionations led to the isolation of two antitumor compounds 5 alpha,8 alpha-epidioxy-24(R)-methylcholesta-6,22… Expand
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Highly Cited
1997
Highly Cited
1997
Fas belongs to the family of type-1 membrane proteins that transduce apoptotic signals. In the present studies, we characterized… Expand
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Highly Cited
1994
Highly Cited
1994
Long-term bone marrow cultures (LTBMC) from patients with multiple myeloma (MM) and normal donors were analyzed for… Expand
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