RPMI-8226

A lymphoblast-like cell line established from the peripheral blood of a 61 year old male patient with multiple myeloma (IgG lambda-type).
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
0102019792017

Papers overview

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2013
2013
OBJECTIVE The present study determined the role of DEP domain containing mTOR-interacting protein (DEPTOR) in the proliferation… (More)
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2012
2012
Multiple myeloma (MM) is the second most commonly diagnosed hematologic malignancy. Although new drugs, including bortezomib and… (More)
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2012
2012
Drug resistance remains a major obstacle to the successful use of chemotherapeutic drugs for many types of cancers including… (More)
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2010
2010
TP-110, a novel proteasome inhibitor, has been found to possess potent growth inhibition in human multiple myeloma cells. To… (More)
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Highly Cited
2009
Highly Cited
2009
Somatically acquired epigenetic changes are present in many cancers. Epigenetic regulation is maintained via post-translational… (More)
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Highly Cited
2007
Highly Cited
2007
Targeting the ubiquitin-proteasome pathway has emerged as a potent anticancer strategy. Bortezomib, a specific proteasome… (More)
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Highly Cited
2002
Highly Cited
2002
The proteasome is a ubiquitous and essential intracellular enzyme that degrades many proteins regulating cell cycle, apoptosis… (More)
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2000
2000
CD95 (Fas/APO-1) is a member of the TNFR superfamily that induces apoptosis following cross-linking with its cognate ligand… (More)
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Highly Cited
1997
Highly Cited
1997
Fas belongs to the family of type-1 membrane proteins that transduce apoptotic signals. In the present studies, we characterized… (More)
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Highly Cited
1994
Highly Cited
1994
Long-term bone marrow cultures (LTBMC) from patients with multiple myeloma (MM) and normal donors were analyzed for… (More)
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