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ROS1 protein, human

Known as: c-Ros Tyrosine Kinase, gp280, c-Ros Receptor Tyrosine Kinase 
Proto-oncogene tyrosine-protein kinase ROS (2347 aa, ~264 kDa) is encoded by the human ROS1 gene. This protein is involved in cell growth, tyrosine… 
National Institutes of Health

Related topics

Related topics

19 relations
Cell Differentiation processCell ProliferationEnzyme GeneLigand Binding

Broader (2)

Protein Tyrosine KinaseProto-Oncogene Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
CEP72‐ROS1: A novel ROS1 oncogenic fusion variant in lung adenocarcinoma identified by next‐generation sequencing
ROS1 rearrangement is a validated therapeutic driver gene in non‐small cell lung cancer (NSCLC) and represents a small subset (1… 
2018
2018
First-in-human study of DS-6051b in patients (pts) with advanced solid tumors (AST) conducted in the US.
2514Background: DS-6051b is an oral, small molecule receptor tyrosine kinase inhibitor with high affinity for ROS1 and NTRK… 
Review
2017
Review
2017
The Plant Cell Reviews Plant Immunity: Receptor-Like Kinases, ROS-RLK Crosstalk, Quantitative Resistance, and the Growth/Defense Trade-Off[OPEN]
Tender green leaves and tasty tubers, roots, and stems are vulnerable to a wide range of pathogens, pests, and herbivores… 
Review
2016
Review
2016
Fusion gene and splice variant analyses in liquid biopsies of lung cancer patients.
Obtaining a biopsy of solid tumors requires invasive procedures that strongly limit patient compliance. In contrast, a blood… 
2015
2015
Tea Polyphenols Protect Against Methylmercury-Induced Cell Injury in Rat Primary Cultured Astrocytes, Involvement of Oxidative Stress and Glutamate Uptake/Metabolism Disorders
Methylmercury (MeHg) is an extremely dangerous environmental contaminant, accumulating preferentially in CNS and causing a series… 
2011
2011
Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2
The poor prognosis and recurrence of HCC are majorly caused by intrahepatic metastasis. Delineating the molecular pathways… 
Review
2011
Review
2011
Variations of specific non-candidate genes and risk of myocardial infarction: a replication study.
1997
1997
Internalization and recycling of glycoprotein 280 in epithelial cells of yolk sac.
The luminal plasma membrane of the epithelial cells lining the visceral layer of the yolk sac and the renal proximal tubule… 
1995
1995
Unusual processing of GP280, a protein associated with the intermicrovillar areas of yolk sac epithelial cells: plasma membrane delivery of immature protein.
We have previously shown the close association with endocytosis of 2 glycoproteins, gp330 and gp280, expressed within the… 
1976
1976
Effects of formylation of vinyl side chains of heme on optical and ligand binding properties of horse heart ferric myoglobin.
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