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ROR1 gene
Known as:
Receptor Tyrosine Kinase-Like Orphan Receptor 1 Gene
, NEUROTROPHIC TYROSINE KINASE, RECEPTOR-RELATED 1
, ROR1
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This gene is thought to play a role in skeletal and cardiac development, but an exact function has yet to be determined.
National Institutes of Health
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Related topics
Related topics
6 relations
Ligand Binding
Phosphorylation
ROR1 protein, human
Receptor Signaling
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma
Tomoya Yamaguchi
,
Miyu Hayashi
,
+10 authors
Takashi Takahashi
Oncogene
2019
Corpus ID: 84185341
The receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a transcriptional target of the lineage-survival oncogene NKX2–1…
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Review
2019
Review
2019
Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways
H. Karvonen
,
Harlan R. Barker
,
Laura Kaleva
,
W. Niininen
,
D. Ungureanu
Cells
2019
Corpus ID: 199449277
Signaling via the Wnt-related receptor tyrosine kinase-like orphan receptor 1 (ROR1) triggers tumorigenic features associated…
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2019
2019
Downregulation of receptor tyrosine kinase-like orphan receptor 1 in preeclampsia placenta inhibits human trophoblast cell proliferation, migration, and invasion by PI3K/AKT/mTOR pathway…
Jie Chen
,
Chongyu Yue
,
+4 authors
Y. Ye
Placenta
2019
Corpus ID: 164932188
Highly Cited
2016
Highly Cited
2016
ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
Tomoya Yamaguchi
,
Can Lu
,
+9 authors
Takashi Takahashi
Nature Communications
2016
Corpus ID: 20879381
The receptor tyrosine kinase-like orphan receptor 1 (ROR1) sustains prosurvival signalling directly downstream of the lineage…
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2016
2016
Receptor tyrosine kinase‐like orphan receptor 1, a target of NKX2‐1/TTF‐1 lineage‐survival oncogene, inhibits apoptosis signal‐regulating kinase 1‐mediated pro‐apoptotic signaling in lung…
L. Ida
,
Tomoya Yamaguchi
,
+4 authors
Takashi Takahashi
Cancer Science
2016
Corpus ID: 11980717
We previously identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) as a transcriptional target of the NKX2‐1/TTF‐1…
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2015
2015
Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia
M. Hojjat-Farsangi
,
M. Jeddi-Tehrani
,
+9 authors
F. Shokri
PLoS ONE
2015
Corpus ID: 17289515
Background ROR1 is a receptor tyrosine kinase expressed in chronic lymphocytic leukemia (CLL) and several other malignancies but…
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Highly Cited
2014
Highly Cited
2014
Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy
Suping Zhang
,
B. Cui
,
+10 authors
T. Kipps
Proceedings of the National Academy of Sciences
2014
Corpus ID: 12535614
Significance This study demonstrates that the oncoembryonic surface antigen, receptor tyrosine kinase-like orphan receptor 1…
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Highly Cited
2012
Highly Cited
2012
NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma.
Tomoya Yamaguchi
,
K. Yanagisawa
,
+8 authors
Takashi Takahashi
Cancer Cell
2012
Corpus ID: 32138248
2010
2010
Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain
Hsiao-Chun Tseng
,
P. Lyu
,
Wen-chang Lin
BMC Cell Biology
2010
Corpus ID: 7294369
BackgroundSeveral receptor tyrosine kinases (RTKs) such as EGFR, FGFR, TRK, and VEGFR are capable of localizing in the cell…
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2005
2005
Comparative genomics on ROR1 and ROR2 orthologs.
Masuko Katoh
,
M. Katoh
Oncology Report
2005
Corpus ID: 44624095
Transmembrane proteins with extracellular Frizzled domain, such as ROR1, ROR2, MUSK, MFRP, FZD1, FZD2, FZD3, FZD4, FZD5, FZD6…
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