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ROR1 gene

Known as: Receptor Tyrosine Kinase-Like Orphan Receptor 1 Gene, NEUROTROPHIC TYROSINE KINASE, RECEPTOR-RELATED 1, ROR1 
This gene is thought to play a role in skeletal and cardiac development, but an exact function has yet to be determined.
National Institutes of Health

Related topics

Related topics

6 relations
Ligand BindingPhosphorylationROR1 protein, humanReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 2635: ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma
TTF-1/NKX2-1, a homeobox-containing transcription factor indispensable for lung morphogenesis, was previously identified by four… 
2019
2019
Blocking ROR1 enhances the roles of erlotinib in lung adenocarcinoma cell lines
Treatment strategies involving tyrosine kinase inhibitors (TKIs) for patients with non-small cell lung cancer (NSCLC) with… 
2018
2018
MicroRNA-27b-3p regulates function and metabolism in insulin resistance cells by inhibiting receptor tyrosine kinase-like orphan receptor 1
Type 2 diabetes mellitus (T2DM) is associated with insulin resistance-induced lipid and glucose metabolism disorder. The study… 
2018
2018
Abstract 106: Shock and ROR! Targeting ROR1 and ROR2 in a preclinical patient-derived model of ovarian cancer
BACKGROUND: New targets for ovarian cancer treatment are critically needed. The Wnt receptors ROR1 and ROR2 are overexpressed in… 
2018
2018
Inhibition of tumor growth by mouse ROR1 specific antibody in a syngeneic mouse tumor model.
2016
2016
Abstract 4585: ROR1 sustains caveolae and RTK-mediated survival signaling as a scaffold of cavin-1 and CAV1 in lung cancer
TTF-1/NKX2-1, a homeobox-containing transcription factor indispensable for lung morphogenesis, was previously identified by four… 
2016
2016
Abstract 4995: anti-ROR1 x anti-CD3 ADAPTIR™ molecule, ES425, redirects T-cell cytotoxicity and inhibits tumor growth in preclinical models of triple-negative breast cancer
Background: Effective treatment of metastatic, triple-negative breast cancer (TNBC) remains a highly unmet medical need. We have… 
2014
2014
Abstract 2083: WNT5a/ROR1 axis in triple-negative breast cancer progression and potential therapy
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Triple negative breast cancer (TNBC) accounts for 15-20… 
2013
2013
Combined ROR1 and CD160 Detection For Improved Minimal Residual Disease In Patients With Chronic Lymphocytic Leukemia (CLL)
Introduction Over the past decade, treatments for patients with chronic lymphocytic leukemia (CLL) have produced complete… 
2005
2005
Comparative genomics on ROR1 and ROR2 orthologs.
Transmembrane proteins with extracellular Frizzled domain, such as ROR1, ROR2, MUSK, MFRP, FZD1, FZD2, FZD3, FZD4, FZD5, FZD6… 
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