ROCK1 gene

Known as: Rho-Associated, Coiled-Coil Containing Protein Kinase 1 Gene, ROCK1, p160-ROCK 
This gene is involved in the regulation of cell division, cytoskeletal remodeling and smooth muscle contraction.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
0102020032017

Papers overview

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2013
2013
Increasing evidence has suggested that dysregulation of certain microRNAs (miRNAs) may contribute to human disease including… (More)
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2012
2012
MicroRNAs are evolutionarily conserved small RNAs that post-transcriptionally regulate gene expression and have emerged as… (More)
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2011
2011
Osteosarcoma is the most common primary malignancy of bone. Patients with localized disease are routinely treated with surgery… (More)
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2011
2011
To determine whether serine/threonine ROCK1 is activated by insulin in vivo in humans and whether impaired activation of ROCK1… (More)
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Highly Cited
2010
Highly Cited
2010
Rho kinases belong to a family of serine/threonine kinases whose role in recruitment and migration of inflammatory cells is… (More)
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2009
2009
Insulin signaling is essential for normal glucose homeostasis. Rho-kinase (ROCK) isoforms have been shown to participate in… (More)
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Highly Cited
2008
Highly Cited
2008
The pattern of microRNA (miRNA) expression is associated with the degree of tumor cell differentiation in human prostate cancer… (More)
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2008
2008
The development of left ventricular cardiomyocyte hypertrophy in response to increased hemodynamic load and neurohormonal stress… (More)
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2006
2006
It has been shown that blockade of Rho kinase with pharmacologic inhibitors inhibits renal fibrosis. This study examined the role… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Rho GTPase and its downstream target, Rho-associated kinase (ROCK), have been implicated in diverse cardiovascular… (More)
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