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ROCK1 gene

Known as: Rho-Associated, Coiled-Coil Containing Protein Kinase 1 Gene, ROCK1, p160-ROCK 
This gene is involved in the regulation of cell division, cytoskeletal remodeling and smooth muscle contraction.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
MicroRNAs (miRNAs) play key roles in cancer development and progression. In the present study, we investigated the role of miR… Expand
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Highly Cited
2012
Highly Cited
2012
Several lines of evidence suggest that mitochondrial dysfunction plays a critical role in the pathogenesis of microvascular… Expand
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Highly Cited
2012
Highly Cited
2012
Background: miRNAs participate in the regulation of skeletal muscle development. Results: miR-148a promotes myogenic… Expand
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Highly Cited
2011
Highly Cited
2011
Purpose: MicroRNAs (miRNA) have been documented playing a critical role in cancer development and progression. In this study, we… Expand
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Highly Cited
2010
Highly Cited
2010
Rho kinases belong to a family of serine/threonine kinases whose role in recruitment and migration of inflammatory cells is… Expand
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Highly Cited
2010
Highly Cited
2010
Cancer cells acquire characteristics of deregulated growth, survival and increased metastatic potential. Genetic mutations that… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT Y-27632, an inhibitor of the Rho-associated kinase ROCK, is a therapeutic lead for Huntington disease (HD). The… Expand
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Highly Cited
2006
Highly Cited
2006
Ventricular myocyte hypertrophy is an important compensatory growth response to pressure overload. However, pathophysiological… Expand
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Highly Cited
2005
Highly Cited
2005
Background— Rho GTPase and its downstream target, Rho-associated kinase (ROCK), have been implicated in diverse cardiovascular… Expand
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Highly Cited
2004
Highly Cited
2004
Vascular smooth muscle cell (SMC) contraction is mediated in part by calcium influx through L-type voltage-gated Ca2+ channels… Expand
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