RNU4-6P gene

The Ntr1 and Ntr2 proteins of Saccharomyces cerevisiae have been reported to interact with proteins involved in pre-mRNA splicing… Expand

The human 25S U4/U6.U5 tri-snRNP is a major building block of the U2-type spliceosome and contains, in addition to the U4, U6… Expand

Activation of the spliceosome for splicing catalysis requires the dissociation of U4 snRNA from the U4/U6 snRNA duplex prior to… Expand

BACKGROUND The dynamic rearrangements of RNA structure which occur during pre-mRNA splicing are thought to be mediated by members… Expand

A systematic study of selectively modified, 36-mer hammerhead ribozymes has resulted in the identification of a generic… Expand

During assembly of the spliceosome, the U4 small nuclear RNA (snRNA) interacts with the spliceosome as a preformed U4/U6-U5… Expand

Human immunodeficiency virus type 1 (HIV-1) encodes a regulatory protein, Rev, which is required for cytoplasmic expression of… Expand

U4 and U6 small nuclear RNAs are associated by an extensive base-pairing interaction that must be disrupted and reformed with… Expand

FIVE small nuclear RNAs (snRNAs) are required for nuclear pre-messenger RNA splicing: Ul, U2, U4, U5 and U61,2. The yeast Ul and… Expand

Structure-function relationships in the vertebrate U4-U6 snRNP have been analysed by assaying the ability of mutant RNAs to form… Expand