• Publications
  • Influence
Evolution of Ribosomal DNA
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Xenopus laevis 28S ribosomal RNA: a secondary structure model and its evolutionary and functional implications.
Based upon the three experimentally derived models of E. coli 23S rRNA (1-3) and the partial model for yeast 26S rRNA (4), which was deduced by homology to E. coli, we derived a secondary structureExpand
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Sequence analysis of 28S ribosomal DNA from the amphibian Xenopus laevis.
We have determined the complete nucleotide sequence of Xenopus laevis 28S rDNA (4110 bp). In order to locate evolutionarily conserved regions within rDNA, we compared the Xenopus 28S sequence toExpand
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Developmental progression of DNA puffs in Sciara coprophila: amplification and transcription.
DNA amplification for two major DNA puffs (II/2B and II/9A) of the fungus fly Sciara coprophila increases steeply from 17 to 19 days after hatching (18 degrees C), resulting in almost 20-fold moreExpand
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Discrete start sites for DNA synthesis in the yeast ARS1 origin.
Sites of DNA synthesis initiation have been detected at the nucleotide level in a yeast origin of bidirectional replication with the use of replication initiation point mapping. The ARS1 origin ofExpand
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Origin recognition complex binding to a metazoan replication origin
The initiation of DNA replication in eukaryotic cells at the onset of S phase requires the origin recognition complex (ORC) [1]. This six-subunit complex, first isolated in Saccharomyces cerevisiaeExpand
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Unusual chromosome movements in sciarid flies.
  • S. Gerbi
  • Biology, Medicine
  • Results and problems in cell differentiation
  • 1986
Sciarid flies are Diptera (two-winged flies) of the suborder Nematocera; the family Sciaridae are commonly known as fungus gnats, since they eat mushrooms and other fungi. MorphologicalExpand
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Replication initiates at a confined region during DNA amplification in Sciara DNA puff II/9A.
Two independent two-dimensional (2D) gel methods were used to map an origin of replication that is developmentally regulated by the steroid hormone ecdysone, namely an origin for DNA puffExpand
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Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication
Nascent strand sequencing (NS-seq) is used to discover DNA replication origins genome-wide, allowing identification of features for their specification. NS-seq depends on the ability of lambdaExpand
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The promoter of DNA puff gene II/9-1 of Sciara coprophila is inducible by ecdysone in late prepupal salivary glands of Drosophila melanogaster.
DNA puffs occur in Sciarid salivary gland chromosomes; they are sites of DNA amplification and intense transcription and they appear to encode secreted structural proteins needed for pupation. InExpand
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