RNF20 gene

Known as: RING FINGER PROTEIN 20, Ring Finger Protein 20, E3 Ubiquitin Protein Ligase Gene, hBRE1 
This gene plays a role in polyubiquitination, histone modification and transcriptional regulation.
National Institutes of Health

Papers overview

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2013
2013
Mixed-lineage leukemia (MLL) fusions are potent oncogenes that initiate aggressive forms of acute leukemia. As aberrant… (More)
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2012
2012
In addition to allelic mutations, cancers are known to harbor alterations in their chromatin landscape. Here we show that genomic… (More)
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2012
2012
Embryonic stem cells (ESCs) maintain high genomic plasticity, which is essential for their capacity to enter diverse… (More)
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Highly Cited
2011
Highly Cited
2011
The E3 ubiquitin ligase RNF20 regulates chromatin structure by monoubiquitinating histone H2B in transcription. Here, we show… (More)
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2011
2011
hBRE1/RNF20 is the major E3 ubiquitin ligase for histone H2B. RNF20 depletion causes a global reduction of monoubiquitylated H2B… (More)
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Review
2011
Review
2011
The DNA damage response (DDR) is emerging as a vast signaling network that temporarily modulates numerous aspects of cellular… (More)
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Highly Cited
2008
Highly Cited
2008
Histone monoubiquitylation is implicated in critical regulatory processes. We explored the roles of histone H2B ubiquitylation in… (More)
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Highly Cited
2005
Highly Cited
2005
In yeast, histone H2B monoubiquitination is a cotranscriptional event regulating histone H3 methylation at lysines 4 and 79… (More)
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2004
2004
An E2 ubiquitin-conjugating enzyme, Rad6, working with an E3 ubiquitin ligase Bre1, catalyzes monoubiquitylation of histone H2B… (More)
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Highly Cited
2003
Highly Cited
2003
Monoubiquitination of histone H2B is required for methylation of histone H3 on lysine 4 (K4), a modification associated with… (More)
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