RNF168 gene

Known as: FLJ35794, RING FINGER PROTEIN 168, RNF168 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
0102020092017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Ubiquitin-dependent signaling during the DNA damage response (DDR) to double-strand breaks (DSBs) is initiated by two E3 ligases… (More)
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Highly Cited
2012
Highly Cited
2012
In response to DNA damage, cells initiate complex signalling cascades leading to growth arrest and DNA repair. The recruitment of… (More)
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Highly Cited
2012
Highly Cited
2012
The ubiquitination cascade has a key role in the assembly of repair and signaling proteins at sites of double-strand DNA breaks… (More)
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2012
2012
Ubiquitination of histones plays a critical role in the regulation of several processes within the nucleus, including maintenance… (More)
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2011
2011
Maintaining genomic integrity is critical to avoid life-threatening disorders, such as premature aging, neurodegeneration and… (More)
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Highly Cited
2010
Highly Cited
2010
The ICP0 protein of herpes simplex virus type 1 is an E3 ubiquitin ligase and transactivator required for the efficient switch… (More)
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Highly Cited
2010
Highly Cited
2010
DNA double-strand breaks (DSBs) pose a potent threat to genome integrity. These lesions also contribute to the efficacy of… (More)
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Highly Cited
2009
Highly Cited
2009
DNA double-strand breaks (DSBs) not only interrupt the genetic information, but also disrupt the chromatin structure, and both… (More)
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Highly Cited
2009
Highly Cited
2009
The biological response to DNA double-strand breaks acts to preserve genome integrity. Individuals bearing inactivating mutations… (More)
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Highly Cited
2009
Highly Cited
2009
Modulation of chromatin structure has emerged as a critical molecular device to control gene expression. Histones undergo… (More)
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