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Retrotransposons have generated about 40 % of the human genome. This review examines the strategies the cell has evolved to… Expand Familial pancreatic cancer (FPC) is a rare hereditary tumor syndrome. The 10-years experience of the national case collection for… Expand OBJECTIVES
To develop a serum-based assay to detect neutralizing antibodies to the xenotropic murine leukemia virus-related virus… Expand Ire1 is an ancient transmembrane sensor of ER stress with dual protein kinase and ribonuclease activities. In response to ER… Expand Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of… Expand Although prostate cancer is the most common non-cutaneous malignancy diagnosed in men in the United States, little is known about… Expand RNASEL (encoding ribonuclease L) has recently been proposed as a candidate for the hereditary prostate cancer (HPC1) gene. We… Expand The RNASEL gene (2',5'-oligoisoadenylate-synthetase dependent) encodes a ribonuclease that mediates the antiviral and apoptotic… Expand ABSTRACT The NS1 protein of influenza A/WSN/33 virus is a 230-amino-acid-long protein which functions as an interferon alpha/beta… Expand The double stranded RNA (dsRNA)-activated protein kinase PKR is a ubiquitously expressed serine/threonine protein kinase that is… Expand