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- Publications
- Influence
SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans
- Rebecca L. Lamason, M. P. Mohideen, +22 authors K. Cheng
- Biology, Medicine
- Science
- 16 December 2005
Lighter variations of pigmentation in humans are associated with diminished number, size, and density of melanosomes, the pigmented organelles of melanocytes. Here we show that zebrafish golden… Expand
Ancient human genomes suggest three ancestral populations for present-day Europeans
- I. Lazaridis, N. Patterson, +117 authors J. Krause
- Biology, Geography
- 2 April 2014
We sequenced genomes from a ∼7,000 year old early farmer from Stuttgart in Germany, an ∼8,000 year old hunter-gatherer from Luxembourg, and seven ∼8,000 year old hunter-gatherers from southern… Expand
Genetic evidence for the convergent evolution of light skin in Europeans and East Asians.
- Heather L. Norton, R. Kittles, +7 authors M. Shriver
- Biology, Medicine
- Molecular biology and evolution
- 20 December 2006
Human skin pigmentation shows a strong positive correlation with ultraviolet radiation intensity, suggesting that variation in skin color is, at least partially, due to adaptation via natural… Expand
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America
To provide a resource for assessing continental ancestry in a wide variety of genetic studies, we identified, validated, and characterized a set of 128 ancestry informative markers (AIMs). The… Expand
Control of confounding of genetic associations in stratified populations.
- C. Hoggart, E. J. Parra, +4 authors P. McKeigue
- Biology, Medicine
- American journal of human genetics
- 1 June 2003
To control for hidden population stratification in genetic-association studies, statistical methods that use marker genotype data to infer population structure have been proposed as a possible… Expand
Skin pigmentation, biogeographical ancestry and admixture mapping
- M. Shriver, E. Parra, +14 authors R. Kittles
- Biology, Medicine
- Human Genetics
- 11 February 2003
Ancestry informative markers (AIMs) are genetic loci showing alleles with large frequency differences between populations. AIMs can be used to estimate biogeographical ancestry at the level of the… Expand
Design and analysis of admixture mapping studies.
- C. Hoggart, M. Shriver, R. Kittles, D. Clayton, P. McKeigue
- Biology, Medicine
- American journal of human genetics
- 1 May 2004
Admixture between populations originating on different continents can be exploited to detect disease susceptibility loci at which risk alleles are distributed differentially between these… Expand
Ancestral proportions and admixture dynamics in geographically defined African Americans living in South Carolina.
- E. Parra, R. Kittles, +12 authors M. Shriver
- Biology, Medicine
- American journal of physical anthropology
- 2001
We analyzed admixture in samples of six different African-American populations from South Carolina: Gullah-speaking Sea Islanders in coastal South Carolina, residents of four counties in the "Low… Expand
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research.
- E. González Burchard, L. Borrell, +12 authors N. Risch
- Sociology, Medicine
- American journal of public health
- 27 October 2005
Latinos are the largest minority population in the United States. Although usually classified as a single ethnic group by researchers, Latinos are heterogeneous from cultural, socioeconomic, and… Expand
cis-Regulatory Changes in Kit Ligand Expression and Parallel Evolution of Pigmentation in Sticklebacks and Humans
- C. T. Miller, S. Beleza, +4 authors D. Kingsley
- Biology, Medicine
- Cell
- 14 December 2007
Dramatic pigmentation changes have evolved within most vertebrate groups, including fish and humans. Here we use genetic crosses in sticklebacks to investigate the parallel origin of pigmentation… Expand