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SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans
Lighter variations of pigmentation in humans are associated with diminished number, size, and density of melanosomes, the pigmented organelles of melanocytes. Here we show that zebrafish goldenExpand
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Ancient human genomes suggest three ancestral populations for present-day Europeans
We sequenced genomes from a ∼7,000 year old early farmer from Stuttgart in Germany, an ∼8,000 year old hunter-gatherer from Luxembourg, and seven ∼8,000 year old hunter-gatherers from southernExpand
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Genetic evidence for the convergent evolution of light skin in Europeans and East Asians.
Human skin pigmentation shows a strong positive correlation with ultraviolet radiation intensity, suggesting that variation in skin color is, at least partially, due to adaptation via naturalExpand
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Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America
To provide a resource for assessing continental ancestry in a wide variety of genetic studies, we identified, validated, and characterized a set of 128 ancestry informative markers (AIMs). TheExpand
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Control of confounding of genetic associations in stratified populations.
To control for hidden population stratification in genetic-association studies, statistical methods that use marker genotype data to infer population structure have been proposed as a possibleExpand
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Skin pigmentation, biogeographical ancestry and admixture mapping
Ancestry informative markers (AIMs) are genetic loci showing alleles with large frequency differences between populations. AIMs can be used to estimate biogeographical ancestry at the level of theExpand
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Design and analysis of admixture mapping studies.
Admixture between populations originating on different continents can be exploited to detect disease susceptibility loci at which risk alleles are distributed differentially between theseExpand
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Ancestral proportions and admixture dynamics in geographically defined African Americans living in South Carolina.
We analyzed admixture in samples of six different African-American populations from South Carolina: Gullah-speaking Sea Islanders in coastal South Carolina, residents of four counties in the "LowExpand
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Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research.
Latinos are the largest minority population in the United States. Although usually classified as a single ethnic group by researchers, Latinos are heterogeneous from cultural, socioeconomic, andExpand
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cis-Regulatory Changes in Kit Ligand Expression and Parallel Evolution of Pigmentation in Sticklebacks and Humans
Dramatic pigmentation changes have evolved within most vertebrate groups, including fish and humans. Here we use genetic crosses in sticklebacks to investigate the parallel origin of pigmentationExpand
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