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RNA Polymerase I
Known as:
DNA-Dependent RNA Polymerase I
, RNA Polymerase A
, Polymerase I, RNA
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A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA…
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National Institutes of Health
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Related topics
Related topics
13 relations
DNA Polymerase I
DNA-Directed RNA Polymerase
DNA-Directed RNA Polymerases I, II, and III Subunit RPABC5
In Blood
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription.
E. Ford
,
R. Voit
,
Gregory B. Liszt
,
C. Magin
,
I. Grummt
,
L. Guarente
Genes & Development
2006
Corpus ID: 12288960
We investigated the role of SIRT7, one of the seven members of the mammalian sirtuin family. We show that SIRT7 is a widely…
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Highly Cited
2005
Highly Cited
2005
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
Azadeh Arabi
,
Siqin Wu
,
+9 authors
A. Wright
Nature Cell Biology
2005
Corpus ID: 26127487
The c-Myc oncoprotein regulates transcription of genes that are associated with cell growth, proliferation and apoptosis. c-Myc…
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Highly Cited
2005
Highly Cited
2005
Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7*
K. Armache
,
Simone Mitterweger
,
A. Meinhart
,
P. Cramer
Journal of Biological Chemistry
2005
Corpus ID: 36440396
We determined the x-ray structure of the RNA polymerase (Pol) II subcomplex Rpb4/7 at 2.3 Å resolution, combined it with a…
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Review
2003
Review
2003
Epigenetic silencing of RNA polymerase I transcription
I. Grummt
,
C. Pikaard
Nature reviews. Molecular cell biology
2003
Corpus ID: 5830782
The genes that encode ribosomal RNA exist in two distinct types of chromatin — an 'open' conformation that is permissive to…
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Highly Cited
2003
Highly Cited
2003
In Exponentially Growing Saccharomyces cerevisiae Cells, rRNA Synthesis Is Determined by the Summed RNA Polymerase I Loading Rate Rather than by the Number of Active Genes
S. French
,
Y. Osheim
,
F. Cioci
,
M. Nomura
,
A. Beyer
Molecular and Cellular Biology
2003
Corpus ID: 19484387
ABSTRACT Genes encoding rRNA are multicopy and thus could be regulated by changing the number of active genes or by changing the…
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Highly Cited
2002
Highly Cited
2002
A Kinetic Framework for a Mammalian RNA Polymerase in Vivo
M. Dundr
,
U. Hoffmann‐Rohrer
,
+4 authors
T. Misteli
Science
2002
Corpus ID: 36392120
We have analyzed the kinetics of assembly and elongation of the mammalian RNA polymerase I complex on endogenous ribosomal genes…
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Highly Cited
1999
Highly Cited
1999
Generation of influenza A viruses entirely from cloned cDNAs.
G. Neumann
,
Tokiko Watanabe
,
+9 authors
Y. Kawaoka
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 37873558
We describe a new reverse-genetics system that allows one to efficiently generate influenza A viruses entirely from cloned cDNAs…
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Highly Cited
1998
Highly Cited
1998
Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I.
Takehiko Kobayashi
,
Denis J. Heck
,
M. Nomura
,
T. Horiuchi
Genes & Development
1998
Corpus ID: 21953754
Saccharomyces cerevisiae carries approximately 150 copies of rDNA in tandem repeats. It was found that the absence of an…
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Highly Cited
1997
Highly Cited
1997
Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance.
Chen Zj
,
C. Pikaard
Genes & Development
1997
Corpus ID: 14651096
Nucleolar dominance is an epigenetic phenomenon that describes nucleolus formation around rRNA genes inherited from only one…
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Highly Cited
1995
Highly Cited
1995
Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product
A. Cavanaugh
,
W. Hempel
,
L. Taylor
,
V. Rogalsky
,
G. Todorov
,
L. Rothblum
Nature
1995
Corpus ID: 4365723
THEprotein encoded by the retinoblastoma susceptibility gene (Rb) functions as a tumour suppressor and negative growth regulator1…
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