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RNA Polymerase I

Known as: DNA-Dependent RNA Polymerase I, RNA Polymerase A, Polymerase I, RNA 
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA… 
National Institutes of Health

Related topics

Related topics

13 relations
DNA Polymerase IDNA-Directed RNA PolymeraseDNA-Directed RNA Polymerases I, II, and III Subunit RPABC5In Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components.
Regulation of ribosome biogenesis is a key element of cell biology, not only because ribosomes are directly required for growth… 
Highly Cited
2005
Highly Cited
2005
Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7*
We determined the x-ray structure of the RNA polymerase (Pol) II subcomplex Rpb4/7 at 2.3 Å resolution, combined it with a… 
Highly Cited
2005
Highly Cited
2005
PTEN Represses RNA Polymerase I Transcription by Disrupting the SL1 Complex
ABSTRACT PTEN is a tumor suppressor whose function is frequently lost in human cancer. It possesses a lipid phosphatase activity… 
Review
2003
Review
2003
Epigenetic silencing of RNA polymerase I transcription
The genes that encode ribosomal RNA exist in two distinct types of chromatin — an 'open' conformation that is permissive to… 
Highly Cited
2003
Highly Cited
2003
In Exponentially Growing Saccharomyces cerevisiae Cells, rRNA Synthesis Is Determined by the Summed RNA Polymerase I Loading Rate Rather than by the Number of Active Genes
ABSTRACT Genes encoding rRNA are multicopy and thus could be regulated by changing the number of active genes or by changing the… 
Highly Cited
2001
Highly Cited
2001
The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1
Highly Cited
2001
Highly Cited
2001
Acetylation of TAFI68, a subunit of TIF‐IB/SL1, activates RNA polymerase I transcription
Mammalian rRNA genes are preceded by a terminator element that is recognized by the transcription termination factor TTF‐I. In… 
Highly Cited
2000
Highly Cited
2000
RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human.
We have cloned a human cDNA that is related to the RNA polymerase I transcription factor Rrn3 of Saccharomyces cerevisiae. The… 
Highly Cited
1997
Highly Cited
1997
Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance.
Nucleolar dominance is an epigenetic phenomenon that describes nucleolus formation around rRNA genes inherited from only one… 
Highly Cited
1993
Highly Cited
1993
Initiation of transcription by RNA polymerase II: a multi-step process.
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