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RIPK3 gene

Known as: RIPK3, RIP3, RECEPTOR-INTERACTING PROTEIN 3 
This gene plays a role in signal transduction and the activation of apoptosis.
National Institutes of Health

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Related topics

6 relations
ApoptosisPhosphorylationRIPK3 protein, humanSerine/Threonine Phosphorylation

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RIPK3 wt Allele

Papers overview

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2019
2019
Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3
Upon necroptosis activation, receptor interacting serine/threonine kinase (RIPK)1 and RIPK3 form a necrosome complex with… 
2016
2016
RIPK3-dependent cell death and inflammasome activation in FLT3-ITD expressing LICs
Acute myeloid leukemia (AML) is sustained by leukemia-initiating cells (LICs) with blocked myeloid differentiation and increased… 
Review
2015
Review
2015
The serine threonine kinase RIP3: lost and found
Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is an essential protein in the “programmed”, or “regulated” necrosis cell… 
Review
2015
Review
2015
Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity.
Receptor-interacting protein kinases 1 and 3 (RIPK1 and RIPK3 ) are homologous serine-threonine kinases that were recognized for… 
2015
2015
A20 is a regulator of necroptosis
The anti-inflammatory molecule A20 inhibits necroptotic cell death by inhibiting ubiquitination of the kinase RIPK3 at the Lys5… 
2015
2015
Ensembling and filtering: an effective and rapid in silico multitarget drug-design strategy to identify RIPK1 and RIPK3 inhibitors
AbstractNecroptosis, a programmed necrosis pathway, is witnessed in diverse human diseases and is primarily regulated by receptor… 
2013
2013
Autophagic cell death RIPs into tumors
The idea of ‘autophagic cell death’ has been the subject of some controversy, much of it focused on links between autophagy and… 
2012
2012
Nuclear Export Signal and Immunodominant CD8+ T Cell Epitope in Influenza A Virus Matrix Protein 1
Shuai Cao et al. recently identified and characterized a nuclear export signal (NES) in influenza A virus matrix protein 1 (M1… 
2007
2007
Cloning, overexpression, purification, and characterization of receptor-interacting protein 3 truncation inEscherichia coli
To facilitate structural studies of receptor-interacting protein 3 (RIP3), we developed a large-scale expression system of a… 
2005
2005
RIP3 beta and RIP3 gamma, two novel splice variants of receptor-interacting protein 3 (RIP3), downregulate RIP3-induced apoptosis.
Receptor-interacting protein 3 (RIP3) is an apoptosis inducing member of the RIP family. Here we report two novel splice variants… 
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