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RIPK3 protein, human

Known as: RIPK3, Receptor-Interacting Serine/Threonine Protein Kinase 3, RIP-Like Protein Kinase 3 
Receptor-interacting serine/threonine-protein kinase 3 (518 aa, ~57 kDa) is encoded by the human RIPK3 gene. This protein plays a role in the… 
National Institutes of Health

Related topics

Related topics

15 relations
ApoptosisEnzyme GenePhosphorylationPhosphotransferases

Broader (2)

Protein-Serine-Threonine KinasesReceptor-Interacting Protein Serine-Threonine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Urotensin-#receptor antagonist SB-706375 protected isolated rat heart from ischaemia–reperfusion injury by attenuating myocardial necrosis via RhoA/ROCK/RIP3 signalling pathway
SB-706375 is a selective receptor antagonist of human urotensin-II (hU-II), which can block the aorta contraction induced by hU… 
2019
2019
Inhibition of PLK1 by capped‐dose volasertib exerts substantial efficacy in MDS and sAML while sparing healthy haematopoiesis
Targeting the cell cycle machinery represents a rational therapeutic approach in myelodysplastic syndromes (MDS) and secondary… 
2019
2019
Loss of receptor interacting protein kinases 3 and caspase‐8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia‐reperfusion injury
Ischaemia‐reperfusion injury (IRI) is associated with programmed cell death that promotes inflammation and organ dysfunction… 
2018
2018
Generation and Use of Chimeric RIP Kinase Molecules to Study Necroptosis.
Necroptosis, a form of regulated necrosis, is triggered by a variety of signals that converge to activate receptor interacting… 
2016
2016
Activation of necroptosis in a rat model of acute respiratory distress syndrome induced by oleic acid.
The present study was aimed to investigate the role of necroptosis in the pathogenesis of acute respiratory distress syndrome… 
2016
2016
Ripoptosome Analysis by Caspase-8 Coimmunoprecipitation.
The biochemical signaling of cell death pathways is executed at a number of different intracellular and/or membrane-bound high… 
2016
2016
New role of E3 ubiquitin ligase in the regulation of necroptosis
Necroptosis is a well-known form of caspase-independent cell death. Necroptosis can be triggered by various extrinsic stimuli… 
2016
2016
RIPK3 Is Largely Dispensable for RIG-I-Like Receptor- and Type I Interferon-Driven Transcriptional Responses to Influenza A Virus in Murine Fibroblasts
The kinase RIPK3 is a key regulator of cell death responses to a growing number of viral and microbial agents. We have found that… 
2014
2014
The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice.
This study aimed to investigate the role of RIP1 and RIP3 in the pathogenesis of aplastic anemia (AA) induced by cyclophosphamide… 
Review
2012
Review
2012
Type 1 interferon-associated necroptosis: a novel mechanism for Salmonella enterica Typhimurium to induce macrophage death
Type 1 interferon-associated necroptosis: a novel mechanism for Salmonella enterica Typhimurium to induce macrophage death 
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