RIPK3 protein, human

Known as: RIPK3, Receptor-Interacting Serine/Threonine Protein Kinase 3, RIP-Like Protein Kinase 3 
Receptor-interacting serine/threonine-protein kinase 3 (518 aa, ~57 kDa) is encoded by the human RIPK3 gene. This protein plays a role in the… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Necroptosis is a form of regulated cell death, which is induced by ligand binding to TNF family death domain receptors, pattern… (More)
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Highly Cited
2014
Highly Cited
2014
Receptor-interacting protein kinase 1 (RIPK1) and RIPK3 trigger pro-inflammatory cell death termed “necroptosis.” Studies with… (More)
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Highly Cited
2014
Highly Cited
2014
Receptor-interacting protein kinase (RIPK)-1 is involved in RIPK3-dependent and -independent signaling pathways leading to cell… (More)
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Highly Cited
2014
Highly Cited
2014
Necroptosis is a form of programmed cell death that depends on the activation of receptor interacting protein kinase-1 (RIPK1… (More)
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Highly Cited
2013
Highly Cited
2013
Caspase-8 deficiency in certain cells prompts chronic inflammation. One mechanism suggested to account for this inflammation is… (More)
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Highly Cited
2012
Highly Cited
2012
Although TRAIL (tumor necrosis factor (TNF)-related apoptosis inducing ligand) is a well-known apoptosis inducer, we have… (More)
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Highly Cited
2012
Highly Cited
2012
The receptor-interacting serine-threonine kinase 3 (RIP3) is a key signaling molecule in the programmed necrosis (necroptosis… (More)
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Highly Cited
2011
Highly Cited
2011
Caspase-8 has two opposing biological functions—it promotes cell death by triggering the extrinsic pathway of apoptosis, but also… (More)
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Review
2010
Review
2010
For a long time, apoptosis was considered the sole form of programmed cell death during development, homeostasis and disease… (More)
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Highly Cited
2009
Highly Cited
2009
Smac mimetics induce apoptosis synergistically with TNF-alpha by triggering the formation of a caspase-8-activating complex… (More)
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