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RET Protein

National Institutes of Health

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7 relations
Ephrin Receptor EphA8MATK geneRET geneRET wt Allele

Broader (2)

Protein Tyrosine KinaseReceptor Protein-Tyrosine Kinases

Narrower (1)

RET protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract B33: CRISPR/Cas9 generation of Ret and Ntrk1 fusion oncogenes and novel in vitro sgRNA screening method
Chromosomal rearrangements of ALK, RET, ROS1, and NTRK1 collectively represent approximately 10% of oncogenic drivers in lung… 
2017
2017
Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro
Previous studies showed that overexposure to manganese causes parkinsonism, a disorder of dopaminergic neurons. Previous studies… 
2014
2014
In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach.
A major challenge remaining in drug design efforts towards protein kinase is due to the development of drug resistance initiated… 
2014
2014
Characterization of wild-type and mutated RET proto- oncogene associated with familial medullary thyroid cancer.
BACKGROUND We aimed to assess RET proto-oncogene polymorphisms in three different Iranian families with medullary thyroid cancer… 
2013
2013
[Invasive properties of papillary thyroid cancer with concurrent BRAF(V600E) mutation and rearranged during transfection proto-oncogene protein expression].
OBJECTIVE To investigate the aggressive properties of papillary thyroid cancer (PTC) with concurrent BRAF(V600E) mutation and… 
2012
2012
Functional analyses of RET mutations in Chinese Hirschsprung disease patients.
BACKGROUND Hirschsprung disease (HSCR) is a congenital disease characterized by the absence of ganglion cells in various length… 
2012
2012
RET: A Multi-Faceted Gene in Human Cancer
Receptor tyrosine kinases (RTK) are transmembrane (TM) proteins featuring an intracellular domain containing the tyrosine kinase… 
Highly Cited
2005
Highly Cited
2005
Evaluation of the RET regulatory landscape reveals the biological relevance of a HSCR-implicated enhancer.
Evolutionary sequence conservation is now a relatively common approach for the prediction of functional DNA sequences. However… 
2002
2002
A new therapeutic approach in medullary thyroid cancer treatment: inhibition of oncogenic RET signaling by adenoviral vector-mediated expression of a dominant-negative RET mutant.
BACKGROUND Mutations in the RET proto-oncogene that result in constitutive tyrosine kinase activity are the underlying cause for… 
1999
1999
No correlation between RET immunostaining and the codon 918 mutation in sporadic medullary thyroid carcinoma
Introduction: Medullary thyroid carcinoma (MTC) occurs sporadically or as part of the inherited cancer syndrome, multiple… 
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