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RET wt Allele

Known as: CDHF12, RET, Gene Rearranged During Transfection 
Human RET wild-type allele is located in the vicinity of 10q11.2 and is approximately 53 kb in length. This allele, which encodes proto-oncogene… 
National Institutes of Health

Related topics

Related topics

22 relations
10q11.2Biologic DevelopmentCCDC6 geneCCDC6 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Differential roles of RET isoforms in medullary and papillary thyroid carcinomas.
The RET receptor tyrosine kinase mediates cell proliferation, survival and migration in embryogenesis and is implicated in the… 
2010
2010
The RET51/FKBP52 complex and its involvement in Parkinson disease.
The tyrosine kinase receptor RET51 is expressed in distinct families of neurons where it promotes different functions. FKBP52 is… 
2009
2009
The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability.
CONTEXT RET is a tyrosine kinase transmembrane receptor expressed in two main alternative isoforms: RET9 and RET51. RET… 
Highly Cited
2006
Highly Cited
2006
Critical and distinct roles for key RET tyrosine docking sites in renal development.
Molecular mechanisms that lead to congenital anomalies of kidneys and the lower urinary tract (CAKUT) are poorly understood. To… 
Highly Cited
2005
Highly Cited
2005
Phosphotyrosine 1062 Is Critical for the In Vivo Activity of the Ret9 Receptor Tyrosine Kinase Isoform
ABSTRACT The receptor tyrosine kinase Ret plays a critical role in the development of the mammalian excretory and enteric nervous… 
Highly Cited
2002
Highly Cited
2002
The Long and Short Isoforms of Ret Function as Independent Signaling Complexes*
Ret, the receptor tyrosine kinase for the glial cell line-derived neurotrophic factor family ligands (GFLs), is alternatively… 
Highly Cited
2001
Highly Cited
2001
C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET
Gain-of-function mutations in the gene encoding the receptor tyrosine kinase RET have been identified as the aetiological factor… 
2000
2000
Relative Expression of the RET9 and RET51 Isoforms in Human Pheochromocytomas
Activating mutations of the RET oncogene cause the inheritance of multiple endocrine neoplasia type 2 (MEN2). The RET pre-mRNA is… 
Highly Cited
1998
Highly Cited
1998
Various mechanisms cause RET-mediated signaling defects in Hirschsprung's disease.
Hirschsprung's disease (HSCR) is a common congenital malformation characterized by the absence of intramural ganglion cells of… 
1998
1998
Expression of RET 3′ splicing variants during human kidney development
The mature mammalian kidney arises through a series of reciprocal inductive interactions between two different cell groups, the… 
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