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RECQL4 protein, human

Known as: RecQ protein-like 4 protein, human, RecQ4 protein, human, RecQ Protein Like 4 
ATP-dependent DNA helicase Q4 (1208 aa, ~133 kDa) is encoded by the human RECQL4 gene. This protein is involved in repair, replication and… 
National Institutes of Health

Related topics

Related topics

18 relations
ATP HydrolysisAdenosine TriphosphatasesBloom syndrome proteinDNA Helicases

Broader (1)

RecQ Helicases

Papers overview

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Highly Cited
2016
Highly Cited
2016
Human Helicase RECQL4 Drives Cisplatin Resistance in Gastric Cancer by Activating an AKT-YB1-MDR1 Signaling Pathway.
Elevation of the DNA-unwinding helicase RECQL4, which participates in various DNA repair pathways, has been suggested to… 
Highly Cited
2013
Highly Cited
2013
Over Expression of Minichromosome Maintenance Genes is Clinically Correlated to Cervical Carcinogenesis
Minichromosome Maintenance (MCM) proteins play important roles in cell cycle progression by mediating DNA replication initiation… 
Highly Cited
2012
Highly Cited
2012
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity
RECQL4 is associated with Rothmund–Thomson Syndrome (RTS), a rare autosomal recessive disorder characterized by premature aging… 
Highly Cited
2011
Highly Cited
2011
RECQL4, the Protein Mutated in Rothmund-Thomson Syndrome, Functions in Telomere Maintenance*
Background: RECQL4 is a RecQ helicase mutated in Rothmund-Thomson Syndrome (RTS) and has a functional role in DNA replication and… 
Highly Cited
2006
Highly Cited
2006
RECQL, a Member of the RecQ Family of DNA Helicases, Suppresses Chromosomal Instability
ABSTRACT The mouse gene Recql is a member of the RecQ subfamily of DEx-H-containing DNA helicases. Five members of this family… 
Highly Cited
2006
Highly Cited
2006
Biochemical characterization of the RECQ4 protein, mutated in Rothmund-Thomson syndrome.
Highly Cited
2005
Highly Cited
2005
Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene
Baller-Gerold syndrome (BGS) is a rare autosomal recessive condition with radial aplasia/hypoplasia and craniosynostosis (OMIM… 
Highly Cited
2004
Highly Cited
2004
RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway.
The Rothmund-Thomson syndrome (growth retardation, skin and bone defects, predisposition to cancer) and the RAPADILINO syndrome… 
Review
2001
Review
2001
Roles of the Bloom's syndrome helicase in the maintenance of genome stability.
The RecQ family of DNA helicases is highly conserved in evolution from bacteria to humans. Of the five known human RecQ family… 
Highly Cited
1999
Highly Cited
1999
Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome
Rothmund-Thomson syndrome (RTS; also known as poikiloderma congenitale) is a rare, autosomal recessive genetic disorder… 
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