RECQL4 protein, human

Known as: RecQ protein-like 4 protein, human, RecQ4 protein, human, RecQ Protein Like 4 
ATP-dependent DNA helicase Q4 (1208 aa, ~133 kDa) is encoded by the human RECQL4 gene. This protein is involved in repair, replication and… (More)
National Institutes of Health

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Review
2012
Review
2012
Helicases are ubiquitous proteins that unwind DNA and participate in DNA metabolism including replication, repair, transcription… (More)
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2012
2012
Telomeres are structures at the ends of chromosomes and are composed of long tracks of short tandem repeat DNA sequences bound by… (More)
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Highly Cited
2009
Highly Cited
2009
In eukaryotes, the activation of the prereplicative complex and assembly of an active DNA unwinding complex are critical but… (More)
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Highly Cited
2009
Highly Cited
2009
Mutations in the RECQL4 gene can lead to three clinical phenotypes with overlapping features. All these syndromes, Rothmund… (More)
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2009
2009
Human RECQL4 protein was expressed in insect cells using a baculovirus protein expression system and it was purified to near… (More)
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Highly Cited
2006
Highly Cited
2006
Baller-Gerold syndrome (BGS) is a rare autosomal recessive condition with radial aplasia/hypoplasia and craniosynostosis (OMIM… (More)
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Highly Cited
2005
Highly Cited
2005
How the replication machinery is loaded at origins of DNA replication is poorly understood. Here, we implicate in this process… (More)
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2005
2005
Rothmund-Thomson syndrome (RTS) is a human genetic disorder characterized by genome instability, cancer susceptibility and… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Rothmund-Thomson syndrome (RTS) is an autosomal recessive disorder associated with an increased predisposition to… (More)
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Highly Cited
1999
Highly Cited
1999
RECQL4 is the fourth gene identified as a member of the human DNA helicase RecQ gene family including the genes for Werner… (More)
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