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RECQL4 protein, human

Known as: RecQ protein-like 4 protein, human, RecQ4 protein, human, RecQ Protein Like 4 
ATP-dependent DNA helicase Q4 (1208 aa, ~133 kDa) is encoded by the human RECQL4 gene. This protein is involved in repair, replication and… 
National Institutes of Health

Related topics

Related topics

18 relations
ATP HydrolysisAdenosine TriphosphatasesBloom syndrome proteinDNA Helicases

Broader (1)

RecQ Helicases

Papers overview

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2015
2015
Fine tuning of a DNA fork by the RecQ helicase
Helicases are enzymes that couple the hydrolysis of ATP to the unwinding of duplex nucleic acids (NAs), thus providing the single… 
2015
2015
A rare RECQL4 indel mutation in a Chinese patient with Rothmund–Thomson syndrome
respectively. Treatments prior to MTX included phototherapy (n = 14, 34.1%), ciclosporin (n = 30, 73.2%, mean duration 21 months… 
Review
2013
Review
2013
Probing Genome Maintenance Functions of human RECQ1
The RecQ helicases are a highly conserved family of DNA-unwinding enzymes that play key roles in protecting the genome stability… 
2013
2013
Long-Term Follow-Up and Molecular Characterization of a Patient with a RECQL4 Mutation Spectrum Disorder
The follow-up of a man from birth to adulthood, presenting with features both of RAPADILINO and Rothmund-Thomson syndrome (RTS… 
Highly Cited
2006
Highly Cited
2006
RECQL4-deficient cells are hypersensitive to oxidative stress/damage: Insights for osteosarcoma prevalence and heterogeneity in Rothmund-Thomson syndrome.
Highly Cited
2006
Highly Cited
2006
Control of Translocations between Highly Diverged Genes by Sgs1, the Saccharomyces cerevisiae Homolog of the Bloom'sSyndrome Protein
ABSTRACT Sgs1 is a RecQ family DNA helicase required for genome stability in Saccharomyces cerevisiae whose human homologs BLM… 
2006
2006
A positive involvement of RecQL4 in UV-induced S-phase arrest.
RecQL4 belongs to a family of conserved RECQ helicases that are important in maintaining chromosomal integrity. Human patients… 
2005
2005
A patient with Rothmund-Thomson syndrome and all features of RAPADILINO.
BACKGROUND Mutations of the human helicase gene RECQL4 have been identified in a subset of patients with Rothmund-Thomson… 
2003
2003
Identification of two novel RECQL4 exonic SNPs and genomic characterization of the IVS12 minisatellite
AbstractRothmund-Thomson syndrome is a rare autosomal recessive disorder characterized by a widely heterogeneous clinical… 
2000
2000
Cloning, genomic structure and chromosomal localization of the gene encoding mouse DNA helicase RecQ helicase protein-like 4.
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