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RAP1GAP gene

Known as: RAP1GAPII, RAP1 GTPase activating protein, KIAA0474 
 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Human chromosome 1p35-p36 has long been suspected to harbor a tumor suppressor gene in pancreatic cancer and other tumors. We… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Cyclic AMP (cAMP) is a well-known intracellular signaling molecule improving barrier function in vascular endothelial… Expand
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Highly Cited
2005
Highly Cited
2005
The Gαo/i-coupled CB1 cannabionoid receptor induces neurite outgrowth in Neuro-2A cells. The mechanisms of signaling through Gαo… Expand
Highly Cited
2004
Highly Cited
2004
Rap1 is a Ras-like guanine-nucleotide-binding protein (GNBP) that is involved in a variety of signal-transduction processes. It… Expand
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Highly Cited
2002
Highly Cited
2002
Rap1 is a small GTPase that is involved in signal transduction cascades. It is highly homologous to Ras but it is down-regulated… Expand
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Highly Cited
2001
Highly Cited
2001
Mechanical force or mechanical stress modulates intracellular signal pathways, including the mitogen-activated protein kinase… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT Rap2 is a member of the Ras family of GTPases and exhibits 60% identity to Rap1, but the function and regulation of Rap2… Expand
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Highly Cited
1999
Highly Cited
1999
Many receptors for neuropeptides and hormones are coupled with the heterotrimeric Gi protein, which activates the p42/44 mitogen… Expand
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Highly Cited
1999
Highly Cited
1999
We used the yeast two-hybrid system to identify proteins that interact directly with Gαo. Mutant-activated Gαo was used as the… Expand
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Highly Cited
1995
Highly Cited
1995
Tuberous sclerosis (TSC) is a human genetic syndrome characterized by the development of benign tumors in a variety of tissues… Expand