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RAP1GAP gene

Known as: RAP1GAPII, RAP1 GTPase activating protein, KIAA0474 
National Institutes of Health

Papers overview

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2018
2018
Reduced expression of Rap1GAP as a prognostic biomarker for primary gastric cancer patients.
BACKGROUND Rap1GAP, a member of the family of GTPase-activating proteins, is reported to be involved in cancer development and… 
2018
2018
Sequential Activation of Rap 1 and Rac 1 Small G Proteins by PDGF Locally at Leading Edges of NIH 3 T 3 Cells
2011
2011
Abstract 3840: Rap1 GTPase activating protein (Rap1GAP) is downregulated in DCIS and invasive ductal carcinoma
Introduction: Rap1 and Rap2, both small GTPases of the Ras family, serve as crucial regulators in cell polarity, adhesion… 
2009
2009
The Roles of Rap1 in Cancer Metastasis and Pancreatic Islet Beta Cell Function
The Roles of Rap1 in Cancer Metastasis and Pancreatic Islet Beta Cell Function by Candice L. Bailey Department of Pharmacology… 
2008
2008
Expression of Rap1GAP in human myeloid disease following microarray selection.
To find the underlying causes of primary myelodysplastic syndrome (MDS), the gene expression profiling of both CD34+ cells and… 
2004
2004
Purification, crystallization and preliminary structural characterization of human Rap1GAP.
Human Rap1GAP, the GTPase-activating protein (GAP) for the small GTPase Rap1, was recombinantly expressed in Escherichia coli… 
1997
1997
Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human.
Sipa1, previously called Spa1, is transcriptionally induced in the murine lymphoid cells following mitogenic stimulation and… 
1996
1996
Comparative analysis and genomic structure of the tuberous sclerosis 2 (TSC2) gene in human and pufferfish.
Germ-line mutations of the TSC2 tumour suppressor gene have been identified in humans with tuberous sclerosis and in the Eker rat… 
1994
1994
RAP1GA1: A candidate tumor suppressor locus in 1p36.1
The rap1/Krev-1 gene (RAP1A) encodes a p21-related protein that suppresses transformation by activated p21{sup ras}. The GTPase… 
Highly Cited
1992
Highly Cited
1992
Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis
rap1GAP is a GTPase-activating protein that specifically stimulates the GTP hydrolytic rate of p21rap1. We have defined the… 
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