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RAP1GAP gene

Known as: RAP1GAPII, RAP1 GTPase activating protein, KIAA0474 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Rap1GAP is a critical tumor suppressor gene that is downregulated in multiple aggressive cancers, such as head and neck squamous… Expand
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Highly Cited
2010
Highly Cited
2010
Thyroid cancer is the most common type of endocrine malignancy, encompassing tumors with various levels of invasive growth and… Expand
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2008
2008
The objective of the current study was to investigate the effects of Rap1GAP on invasion and progression of head and neck… Expand
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Highly Cited
2005
Highly Cited
2005
Cyclic AMP (cAMP) is a well-known intracellular signaling molecule improving barrier function in vascular endothelial cells. Here… Expand
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Highly Cited
2004
Highly Cited
2004
Rap1 is a Ras-like guanine-nucleotide-binding protein (GNBP) that is involved in a variety of signal-transduction processes. It… Expand
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2002
2002
Rap1 is a small GTPase that is involved in signal transduction cascades. It is highly homologous to Ras but it is down-regulated… Expand
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Highly Cited
2002
Highly Cited
2002
Endothelial cell migration is an essential step in vasculogenesis and angiogenesis, in which receptor tyrosine kinases play a… Expand
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Highly Cited
2001
Highly Cited
2001
Mechanical force or mechanical stress modulates intracellular signal pathways, including the mitogen-activated protein kinase… Expand
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Highly Cited
2000
Highly Cited
2000
Rap2 is a member of the Ras family of GTPases and exhibits 60% identity to Rap1, but the function and regulation of Rap2 remain… Expand
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Highly Cited
1999
Highly Cited
1999
We used the yeast two-hybrid system to identify proteins that interact directly with Galpha(o). Mutant-activated Galpha(o) was… Expand
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